UniProt Q0SXH8

Cytochrome b(562),Smoothened homolog (Q0SXH8)

Cytochrome b(562),Smoothened homolog (UniProt Q0SXH8): 2 experimental structures on GenesisL1, 3 ligands bound, 12 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: Q0SXH8
Protein: Cytochrome b(562),Smoothened homolog
Experimental structures: 2
Predicted models: 0
Ligands: 3
Pockets: 12 · 2 records with a druggable one

Structures

2 records of Q0SXH8 in the MolNFT archive: 2 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
4N4W	Structure of the human smoothened receptor in complex with SANT-1.	x-ray diffraction	A	NAG, SNT, ZN	6 (best 0.85)
4N4W	Structure of the human smoothened receptor in complex with sant-1.	x-ray diffraction	A	NAG, SNT, ZN	6 (best 0.85)

Ligands

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
SNT · (E)-N-(4-benzylpiperazin-1-yl)-1-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methanimine · in 2 records
ZN · Zinc ion · in 2 records

Experiment against prediction

4N4W chain A against the predicted model Q99835: TM-score 0.76, RMSD 1.87 Å
4N4W chain A against the predicted model Q99835: TM-score 0.76, RMSD 1.87 Å

Elsewhere

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