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UniProt Q0P7K6

Beta-lactamase (Q0P7K6)

Beta-lactamase (UniProt Q0P7K6), EC 3.5.2.6: 3 experimental structures on GenesisL1, 7 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q0P7K6
Protein
Beta-lactamase
EC
3.5.2.6
Experimental structures
3
Predicted models
0
Ligands
7
Pockets
16 · 3 records with a druggable one

Structures

3 records of Q0P7K6 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7MDCFull-length wildtype ClbP inhibited by hexanoyl-D-asparagine boronic acidx-ray diffractionA97N, YX7, SO4, CL3 (best 0.57)
7MDFFull-length S95A ClbP bound to N-acyl-D-asparagine analogx-ray diffractionAZ9A, Z9G, AV0, 97N, SO4, CL3 (best 0.58)
7UL6CryoEM structure of full-length dimeric ClbPelectron microscopyA, B—10 (best 0.58)

Ligands

  • 97N · (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate · in 2 records
  • CL · Chloride ion · in 2 records
  • SO4 · Sulfate ion · in 2 records
  • AV0 · 2-decyl-2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}dodecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside · in 1 record
  • YX7 · [(1S)-3-amino-1-(hexanoylamino)-3-oxopropyl]boronic acid · in 1 record
  • Z9A · methyl N~2~-[4-(4-bromophenyl)butanoyl]-D-asparaginyl-L-alaninate · in 1 record
  • Z9G · N~2~-[4-(4-bromophenyl)butanoyl]-D-asparagine · in 1 record

Elsewhere

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