UniProt Q09734
Macrophage infectivity potentiator (Q09734)
Macrophage infectivity potentiator (UniProt Q09734), EC 5.2.1.8: 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q09734
- Protein
- Macrophage infectivity potentiator
- EC
- 5.2.1.8
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
4 records of Q09734 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JVW | Trypanosoma cruzi macrophage infectivity potentiator (tcmip) | x-ray diffraction | A | — | — |
| 1JVW | Trypanosoma cruzi macrophage infectivity potentiator (tcmip) | x-ray diffraction | A | — | — |
| 8P42 | Full length structure of TcMIP with bound inhibitor NJS227. | x-ray diffraction | A, D | WRX | 4 (best 0.61) |
| Q09734 | AlphaFold monomer V2.0 prediction for macrophage infectivity potentiator (Q09734) | predicted | A | — | — |
Ligands
- WRX · (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-(pyridin-3-ylmethylamino)propan-2-yl]piperidine-2-carboxamide · in 1 record
Experiment against prediction
- 1JVW chain A against the predicted model Q09734: TM-score 0.98, RMSD 0.97 Å
- 1JVW chain A against the predicted model Q09734: TM-score 0.98, RMSD 0.97 Å
- 8P42 chain A against the predicted model Q09734: TM-score 0.98, RMSD 0.71 Å
- 8P42 chain D against the predicted model Q09734: TM-score 0.97, RMSD 0.95 Å
Elsewhere
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