UniProt Q08746
Regulator of ribosome biosynthesis (Q08746)
Regulator of ribosome biosynthesis (UniProt Q08746): 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q08746
- Protein
- Regulator of ribosome biosynthesis
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 7 records with a druggable one
Structures
14 records of Q08746 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCT | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | electron microscopy | w | — | — |
| 5A53 | Crystal Structure of the Rpf2-Rrs1 complex | x-ray diffraction | A, B | SO4 | 3 (best 0.60) |
| 5A53 | Crystal structure of the RPF2-RRS1 complex | x-ray diffraction | A, B | — | — |
| 5WXL | Crystal structure of the Rrs1 and Rpf2 complex | x-ray diffraction | B, D | — | 6 (best 0.66) |
| 5WXL | Crystal structure of the RRS1 and RPF2 complex | x-ray diffraction | B, D | — | — |
| 6FT6 | Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors | electron microscopy | w | — | 1 (best 0.85) |
| 6M62 | Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta… | electron microscopy | w | — | — |
| 7BT6 | Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.12… | electron microscopy | w | — | 2 (best 0.83) |
| 7BTB | Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22… | electron microscopy | w | — | 1 (best 0.84) |
| 7OH3 | Nog1-TAP associated immature ribosomal particle population B from S. cerevisiae | electron microscopy | w | — | — |
| 7OHQ | Nog1-TAP associated immature ribosomal particle population C from S. cerevisiae | electron microscopy | w | — | 1 (best 0.85) |
| 7OHT | Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL2 expression shut… | electron microscopy | w | — | 3 (best 0.85) |
| 7UG6 | Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 | electron microscopy | w | — | — |
| Q08746 | AlphaFold monomer V2.0 prediction for regulator of ribosome biosynthesis (Q08746) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 5A53 chain A against the predicted model Q08746: TM-score 0.94, RMSD 0.86 Å
- 5A53 chain A against the predicted model Q08746: TM-score 0.94, RMSD 0.86 Å
- 5WXL chain B against the predicted model Q08746: TM-score 0.94, RMSD 1.09 Å
- 5WXL chain B against the predicted model Q08746: TM-score 0.94, RMSD 1.09 Å
- 6M62 chain w against the predicted model Q08746: TM-score 0.61, RMSD 3.78 Å
- 7UG6 chain w against the predicted model Q08746: TM-score 0.61, RMSD 3.86 Å
- 7OHQ chain w against the predicted model Q08746: TM-score 0.61, RMSD 3.86 Å
- 7OH3 chain w against the predicted model Q08746: TM-score 0.61, RMSD 4.20 Å
- 7OHT chain w against the predicted model Q08746: TM-score 0.61, RMSD 4.16 Å
- 3JCT chain w against the predicted model Q08746: TM-score 0.61, RMSD 3.92 Å
Elsewhere
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