UniProt Q08603
Geranylgeranyl transferase type-2 subunit beta (Q08603)
Geranylgeranyl transferase type-2 subunit beta (UniProt Q08603): 42 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q08603
- Protein
- Geranylgeranyl transferase type-2 subunit beta
- Experimental structures
- 42
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
43 records of Q08603 in the MolNFT archive: 42 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DCE | Crystal structure of rab geranylgeranyltransferase from rat brain | x-ray diffraction | B, D | — | — |
| 1DCE | Crystal structure of rab geranylgeranyltransferase from rat brain | x-ray diffraction | B, D | — | — |
| 1LTX | Structure of Rab Escort Protein-1 in complex with Rab geranylgeranyl transferase and isoprenoid | x-ray diffraction | B | — | — |
| 1LTX | Structure of rab escort protein-1 in complex with rab geranylgeranyl transferase and isoprenoid | x-ray diffraction | B | — | — |
| 3C72 | Engineered RabGGTase in complex with a peptidomimetic inhibitor | x-ray diffraction | B | — | — |
| 3C72 | Engineered rabggtase in complex with a peptidomimetic inhibitor | x-ray diffraction | B | — | — |
| 3DSS | Crystal structure of RabGGTase(DELTA LRR; DELTA IG) | x-ray diffraction | B | — | — |
| 3DSS | Crystal structure of RABGGTASE(DELTA lrr; delta ig) | x-ray diffraction | B | — | — |
| 3DST | Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with geranylgeranyl pyrophosphate | x-ray diffraction | B | — | — |
| 3DST | Crystal structure of RABGGTASE(DELTA lrr; delta IG)IN complex with geranylgeranyl pyrophosphate | x-ray diffraction | B | — | — |
| 3DSU | Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with farnesyl pyrophosphate | x-ray diffraction | B | — | — |
| 3DSU | Crystal structure of RABGGTASE(DELTA lrr; delta IG)IN complex with farnesyl pyrophosphate | x-ray diffraction | B | — | — |
| 3DSV | Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with mono-prenylated peptide… | x-ray diffraction | B | — | — |
| 3DSV | Crystal structure of RABGGTASE(DELTA lrr; delta IG)IN complex with mono-prenylated peptide… | x-ray diffraction | B | — | — |
| 3DSW | Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with mono-prenylated peptide… | x-ray diffraction | B | — | — |
| 3DSW | Crystal structure of RABGGTASE(DELTA lrr; delta IG)IN complex with mono-prenylated peptide… | x-ray diffraction | B | — | — |
| 3DSX | Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with di-prenylated peptide… | x-ray diffraction | B | — | — |
| 3DSX | Crystal structure of RABGGTASE(DELTA lrr; delta IG)IN complex with di- prenylated peptide… | x-ray diffraction | B | — | — |
| 3HXB | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 6) | x-ray diffraction | B | — | — |
| 3HXB | Engineered rabggtase in complex with a peptidomimetic inhibitor (compound 6) | x-ray diffraction | B | — | — |
| 3HXC | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 8) | x-ray diffraction | B | — | — |
| 3HXC | Engineered rabggtase in complex with a peptidomimetic inhibitor (compound 8) | x-ray diffraction | B | — | — |
| 3HXD | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 9) | x-ray diffraction | B | — | — |
| 3HXD | Engineered rabggtase in complex with a peptidomimetic inhibitor (compound 9) | x-ray diffraction | B | — | — |
| 3HXE | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 37) | x-ray diffraction | B | — | — |
| 3HXE | Engineered rabggtase in complex with a peptidomimetic inhibitor (compound 37) | x-ray diffraction | B | — | — |
| 3HXF | Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 32) | x-ray diffraction | B | — | — |
| 3HXF | Engineered rabggtase in complex with a peptidomimetic inhibitor (compound 32) | x-ray diffraction | B | — | — |
| 3PZ1 | Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 | x-ray diffraction | B | — | — |
| 3PZ1 | Crystal structure of RABGGTASE(DELTA lrr; delta ig) in complex with BMS3 | x-ray diffraction | B | — | — |
| 3PZ2 | Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 and lipid substrate GGPP | x-ray diffraction | B | — | — |
| 3PZ2 | Crystal structure of RABGGTASE(DELTA lrr; delta ig) in complex with BMS3 and lipid substrate ggpp | x-ray diffraction | B | — | — |
| 3PZ3 | Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS-analogue 14 | x-ray diffraction | B | — | — |
| 3PZ3 | Crystal structure of RABGGTASE(DELTA lrr; delta ig) in complex with bms-analogue 14 | x-ray diffraction | B | — | — |
| 4EHM | RabGGTase in complex with covalently bound Psoromic acid | x-ray diffraction | B | — | — |
| 4EHM | Rabggtase in complex with covalently bound psoromic acid | x-ray diffraction | B | — | — |
| 4GTS | Engineered RabGGTase in complex with BMS analogue 16 | x-ray diffraction | B | — | — |
| 4GTS | Engineered rabggtase in complex with bms analogue 16 | x-ray diffraction | B | — | — |
| 4GTT | Engineered RabGGTase in complex with BMS analogue 12 | x-ray diffraction | B | — | — |
| 4GTT | Engineered rabggtase in complex with bms analogue 12 | x-ray diffraction | B | — | — |
| 4GTV | Engineered RabGGTase in complex with BMS analogue 13 | x-ray diffraction | B | — | — |
| 4GTV | Engineered rabggtase in complex with bms analogue 13 | x-ray diffraction | B | — | — |
| Q08603 | AlphaFold monomer V2.0 prediction for geranylgeranyl transferase type-2 subunit beta (Q08603) | predicted | A | — | 2 (best 0.68) |
Experiment against prediction
- 3HXF chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.55 Å
- 3HXF chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.55 Å
- 3PZ3 chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.56 Å
- 3PZ3 chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.56 Å
- 3DSV chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.58 Å
- 3DSV chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.58 Å
- 4GTS chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.57 Å
- 4GTS chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.57 Å
- 3DST chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.59 Å
- 3DST chain B against the predicted model Q08603: TM-score 0.99, RMSD 0.59 Å
Elsewhere
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