UniProt Q08282
Leucine carboxyl methyltransferase 2 (Q08282)
Leucine carboxyl methyltransferase 2 (UniProt Q08282), EC 2.1.1.-: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 109 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q08282
- Protein
- Leucine carboxyl methyltransferase 2
- EC
- 2.1.1.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 109 · 7 records with a druggable one
Structures
7 records of Q08282 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ZW9 | Crystal structure of tRNA wybutosine synthesizing enzyme TYW4 | x-ray diffraction | A, B | SAM | 16 (best 0.76) |
| 2ZW9 | Crystal structure of tRNA wybutosine synthesizing enzyme TYW4 | x-ray diffraction | A, B | SAM | 16 (best 0.76) |
| 2ZWA | Crystal structure of tRNA wybutosine synthesizing enzyme TYW4 | x-ray diffraction | A, B | SAH | 18 (best 0.76) |
| 2ZWA | Crystal structure of tRNA wybutosine synthesizing enzyme TYW4 | x-ray diffraction | A, B | SAH | 18 (best 0.76) |
| 2ZZK | Crystal structure of tRNA wybutosine synthesizing enzyme TYW4 | x-ray diffraction | A, B | — | 17 (best 0.75) |
| 2ZZK | Crystal structure of tRNA wybutosine synthesizing enzyme TYW4 | x-ray diffraction | A, B | — | 17 (best 0.75) |
| Q08282 | AlphaFold monomer V2.0 prediction for tRNA wybutosine-synthesizing protein 4 (Q08282) | predicted | A | — | 7 (best 0.74) |
Ligands
Experiment against prediction
- 2ZW9 chain A against the predicted model Q08282: TM-score 0.99, RMSD 1.01 Å
- 2ZW9 chain A against the predicted model Q08282: TM-score 0.99, RMSD 1.01 Å
- 2ZW9 chain B against the predicted model Q08282: TM-score 0.99, RMSD 1.10 Å
- 2ZW9 chain B against the predicted model Q08282: TM-score 0.99, RMSD 1.10 Å
- 2ZWA chain A against the predicted model Q08282: TM-score 0.98, RMSD 1.41 Å
- 2ZWA chain A against the predicted model Q08282: TM-score 0.98, RMSD 1.41 Å
- 2ZZK chain A against the predicted model Q08282: TM-score 0.96, RMSD 1.72 Å
- 2ZZK chain A against the predicted model Q08282: TM-score 0.96, RMSD 1.72 Å
- 2ZZK chain B against the predicted model Q08282: TM-score 0.96, RMSD 1.68 Å
- 2ZZK chain B against the predicted model Q08282: TM-score 0.96, RMSD 1.68 Å
Elsewhere
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