UniProt Q08235
Ribosome biogenesis protein BRX1 (Q08235)
Ribosome biogenesis protein BRX1 (UniProt Q08235): 19 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q08235
- Protein
- Ribosome biogenesis protein BRX1
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 5 records with a druggable one
Structures
20 records of Q08235 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5Z1G | Structure of the Brx1 and Ebp2 complex | x-ray diffraction | B, D | SO4 | — |
| 5Z1G | Structure of the BRX1 and EBP2 complex | x-ray diffraction | B, D | SO4 | — |
| 5Z3G | Cryo-EM structure of a nucleolar pre-60S ribosome (RPF1-tap) | electron microscopy | a | — | — |
| 6CB1 | Yeast nucleolar pre-60S ribosomal subunit (state 3) | electron microscopy | b | — | — |
| 6CB1 | Yeast nucleolar pre-60S ribosomal subunit (state 3) | electron microscopy | b | — | — |
| 6ELZ | State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | electron microscopy | A | — | — |
| 6EM3 | State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | A | — | — |
| 6EM3 | State a architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | A | — | — |
| 6EM4 | State B architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | A | — | — |
| 6EM5 | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | A | — | 1 (best 0.72) |
| 6EM5 | State D architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | A | — | — |
| 7NAC | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | electron microscopy | A | — | — |
| 7OHR | Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae | electron microscopy | A | — | — |
| 7OHS | Nog1-TAP associated immature ribosomal particle population F from S. cerevisiae | electron microscopy | A | — | 2 (best 0.86) |
| 7R7A | State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model | electron microscopy | A | — | — |
| 7R7C | State E2 nucleolar 60S ribosomal biogenesis intermediate - L1 stalk local model | electron microscopy | A | — | 3 (best 0.81) |
| 8E5T | Yeast co-transcriptional Noc1-Noc2 RNP assembly checkpoint intermediate | electron microscopy | b | — | 1 (best 0.76) |
| 8V83 | 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) | electron microscopy | A | — | 2 (best 0.82) |
| 8V84 | 60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) | electron microscopy | A | — | — |
| Q08235 | AlphaFold monomer V2.0 prediction for ribosome biogenesis protein BRX1 (Q08235) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 5Z1G chain D against the predicted model Q08235: TM-score 0.99, RMSD 0.63 Å
- 5Z1G chain D against the predicted model Q08235: TM-score 0.99, RMSD 0.63 Å
- 5Z1G chain B against the predicted model Q08235: TM-score 0.98, RMSD 0.83 Å
- 5Z1G chain B against the predicted model Q08235: TM-score 0.98, RMSD 0.83 Å
- 6ELZ chain A against the predicted model Q08235: TM-score 0.98, RMSD 0.77 Å
- 6EM5 chain A against the predicted model Q08235: TM-score 0.98, RMSD 0.77 Å
- 6EM5 chain A against the predicted model Q08235: TM-score 0.98, RMSD 0.77 Å
- 7OHR chain A against the predicted model Q08235: TM-score 0.97, RMSD 0.88 Å
- 5Z3G chain a against the predicted model Q08235: TM-score 0.96, RMSD 1.07 Å
- 8E5T chain b against the predicted model Q08235: TM-score 0.95, RMSD 1.39 Å
Elsewhere
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