UniProt Q08211
ATP-dependent RNA helicase A (Q08211)
ATP-dependent RNA helicase A (UniProt Q08211), EC 3.6.4.13: 7 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q08211
- Protein
- ATP-dependent RNA helicase A
- EC
- 3.6.4.13
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 1 record with a druggable one
Structures
8 records of Q08211 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3LLM | Crystal Structure Analysis of a RNA Helicase | x-ray diffraction | A, B | — | — |
| 3LLM | Crystal structure analysis of a RNA helicase | x-ray diffraction | A, B | — | — |
| 3VYX | Structural insights into RISC assembly facilitated by dsRNA binding domains of human RNA helicase… | x-ray diffraction | A | — | — |
| 3VYX | Structural insights into risc assembly facilitated by dsrna binding domains of human RNA helicase… | x-ray diffraction | A | — | — |
| 3VYY | Structural insights into RISC assembly facilitated by dsRNA binding domains of human RNA helicase A… | x-ray diffraction | A, B | — | — |
| 3VYY | Structural insights into risc assembly facilitated by dsrna binding domains of human RNA helicase a… | x-ray diffraction | A, B | — | — |
| 8SZP | Human DHX9 bound to ADP | x-ray diffraction | A, B | ADP, MG, SO4 | 20 (best 0.84) |
| Q08211 | AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase a (Q08211) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3LLM chain B against the predicted model Q08211: TM-score 0.99, RMSD 0.62 Å
- 3LLM chain B against the predicted model Q08211: TM-score 0.99, RMSD 0.62 Å
- 3LLM chain A against the predicted model Q08211: TM-score 0.98, RMSD 0.87 Å
- 3LLM chain A against the predicted model Q08211: TM-score 0.98, RMSD 0.87 Å
- 3VYX chain A against the predicted model Q08211: TM-score 0.96, RMSD 0.93 Å
- 3VYX chain A against the predicted model Q08211: TM-score 0.96, RMSD 0.93 Å
- 8SZP chain B against the predicted model Q08211: TM-score 0.95, RMSD 2.36 Å
- 3VYY chain B against the predicted model Q08211: TM-score 0.94, RMSD 1.31 Å
- 3VYY chain B against the predicted model Q08211: TM-score 0.94, RMSD 1.31 Å
- 8SZP chain A against the predicted model Q08211: TM-score 0.93, RMSD 2.90 Å
Elsewhere
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