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UniProt Q07387

SIV protease (Q07387)

SIV protease (UniProt Q07387), EC 3.4.23.16: 4 experimental structures on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q07387
Protein
SIV protease
EC
3.4.23.16
Experimental structures
4
Predicted models
0
Ligands
2
Pockets
4 · 4 records with a druggable one

Structures

4 records of Q07387 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1SIVThree-dimensional structure of a SIV PROTEASE(SLASH)INHIBITOR complex. implications for the design…x-ray diffractionA, BPSI1 (best 0.70)
1SIVThree-dimensional structure of a SIV PROTEASE(SLASH)INHIBITOR complex. implications for the design…x-ray diffractionA, BPSI1 (best 0.70)
1TCWSIV protease complexed with inhibitor SB203386x-ray diffractionA, BIM11 (best 0.73)
1TCWSIV protease complexed with inhibitor SB203386x-ray diffractionA, BIM11 (best 0.73)

Ligands

  • IM1 · (2R,4S,5S,1'S)-2-phenylmethyl-4-hydroxy-5-(tert-butoxycarbonyl)amino-6-phenyl hexanoyl-N-(1'-imidazo-2-yl)-2'-methylpropanamide · in 2 records
  • PSI · methyl N-{(4S,5S)-5-[(L-alanyl-L-alanyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-valyl-L-valinate · in 2 records

Elsewhere

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