UniProt Q07296
Phosphoribosylaminoimidazole-succinocarboxamide synthase (Q07296)
Phosphoribosylaminoimidazole-succinocarboxamide synthase (UniProt Q07296): 6 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q07296
- Protein
- Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
7 records of Q07296 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4FE2 | X-Ray Structure of SAICAR Synthetase (PurC) from Streptococcus pneumoniae complexed with AIR, ADP… | x-ray diffraction | A, B | — | — |
| 4FE2 | X-ray structure of saicar synthetase (purc) from streptococcus pneumoniae complexed with air, ADP… | x-ray diffraction | A, B | — | — |
| 4FGR | X-Ray Structure of SAICAR Synthetase (PurC) from Streptococcus pneumoniae complexed with ADP and… | x-ray diffraction | A, B | — | — |
| 4FGR | X-ray structure of saicar synthetase (purc) from streptococcus pneumoniae complexed with ADP and… | x-ray diffraction | A, B | — | — |
| 4NYE | Structures of SAICAR Synthetase (PurC) from Streptococcus pneumoniae with ADP, Mg2+, AIR and L-Asp | x-ray diffraction | A, B | — | — |
| 4NYE | Structures of saicar synthetase (purc) from streptococcus pneumoniae with ADP, MG2+, air and L-asp | x-ray diffraction | A, B | — | — |
| Q07296 | AlphaFold monomer V2.0 prediction for phosphoribosylaminoimidazole- succinocarboxamide synthase… | predicted | A | — | 1 (best 0.76) |
Experiment against prediction
- 4FE2 chain B against the predicted model Q07296: TM-score 0.99, RMSD 0.51 Å
- 4FE2 chain B against the predicted model Q07296: TM-score 0.99, RMSD 0.51 Å
- 4FE2 chain A against the predicted model Q07296: TM-score 0.99, RMSD 0.41 Å
- 4FE2 chain A against the predicted model Q07296: TM-score 0.99, RMSD 0.41 Å
- 4NYE chain B against the predicted model Q07296: TM-score 0.99, RMSD 0.64 Å
- 4NYE chain B against the predicted model Q07296: TM-score 0.99, RMSD 0.64 Å
- 4FGR chain B against the predicted model Q07296: TM-score 0.99, RMSD 0.64 Å
- 4FGR chain B against the predicted model Q07296: TM-score 0.99, RMSD 0.64 Å
- 4NYE chain A against the predicted model Q07296: TM-score 0.99, RMSD 0.90 Å
- 4NYE chain A against the predicted model Q07296: TM-score 0.99, RMSD 0.90 Å
Elsewhere
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