UniProt Q06787
Fragile X mental retardation protein 1 (Q06787)
Fragile X mental retardation protein 1 (UniProt Q06787): 17 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q06787
- Protein
- Fragile X mental retardation protein 1
- Experimental structures
- 17
- Predicted models
- 1
Structures
18 records of Q06787 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BKD | Structure of the N-terminal domain of Fragile X Mental Retardation Protein | solution nmr | N | — | — |
| 2BKD | Structure of the N-terminal domain of fragile X mental retardation protein | solution nmr | N | — | — |
| 2FMR | KH1 from the fragile X protein FMR1, NMR, 18 structures | solution nmr | A | — | — |
| 2FMR | KH1 from the fragile X protein FMR1, NMR, 18 structures | solution nmr | A | — | — |
| 2LA5 | RNA Duplex-Quadruplex Junction Complex with FMRP RGG peptide | solution nmr | B | — | — |
| 2LA5 | RNA duplex-quadruplex junction complex with fmrp rgg peptide | solution nmr | B | — | — |
| 4OVA | Structure of the two tandem Tudor domains and a new identified KH0 domain from human Fragile X… | x-ray diffraction | A, B, C, D | — | — |
| 4OVA | Structure of the two tandem tudor domains and a new identified KH0 domain from human fragile X… | x-ray diffraction | A, B, C, D | — | — |
| 4QVZ | FMRP N-terminal domain | x-ray diffraction | A, B | — | — |
| 4QVZ | Fmrp N-terminal domain | x-ray diffraction | A, B | — | — |
| 4QW2 | FMRP N-terminal domain (R138Q) | x-ray diffraction | A, B | — | — |
| 4QW2 | Fmrp N-terminal domain (R138Q) | x-ray diffraction | A, B | — | — |
| 5DE5 | Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA. | x-ray diffraction | B, D | — | — |
| 5DE5 | Crystal structure of the complex between human fmrp rgg motif and G- quadruplex RNA. | x-ray diffraction | B, D | — | — |
| 5DE8 | Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium… | x-ray diffraction | B, D | — | — |
| 5DE8 | Crystal structure of the complex between human fmrp rgg motif and G- quadruplex RNA, iridium… | x-ray diffraction | B, D | — | — |
| 5DEA | Crystal structure of the complex between human fmrp rgg motif and G- quadruplex RNA, cesium bound… | x-ray diffraction | B, D | — | — |
| Q06787 | AlphaFold monomer V2.0 prediction for synaptic functional regulator FMR1 (Q06787) | predicted | A | — | — |
Experiment against prediction
- 4QW2 chain A against the predicted model Q06787: TM-score 0.99, RMSD 0.56 Å
- 4QW2 chain A against the predicted model Q06787: TM-score 0.99, RMSD 0.56 Å
- 4OVA chain C against the predicted model Q06787: TM-score 0.98, RMSD 0.82 Å
- 4OVA chain C against the predicted model Q06787: TM-score 0.98, RMSD 0.82 Å
- 4QVZ chain A against the predicted model Q06787: TM-score 0.98, RMSD 0.78 Å
- 4QVZ chain A against the predicted model Q06787: TM-score 0.98, RMSD 0.78 Å
- 4OVA chain A against the predicted model Q06787: TM-score 0.98, RMSD 0.93 Å
- 4OVA chain A against the predicted model Q06787: TM-score 0.98, RMSD 0.93 Å
- 4OVA chain D against the predicted model Q06787: TM-score 0.98, RMSD 0.92 Å
- 4OVA chain D against the predicted model Q06787: TM-score 0.98, RMSD 0.92 Å
Elsewhere
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