UniProt Q06162
Inner kinetochore subunit NKP2 (Q06162)
Inner kinetochore subunit NKP2 (UniProt Q06162): 7 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q06162
- Protein
- Inner kinetochore subunit NKP2
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
8 records of Q06162 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NUW | Yeast CTF19 complex | electron microscopy | J | — | — |
| 6QLD | Structure of inner kinetochore CCAN-Cenp-A complex | electron microscopy | Z | — | — |
| 6QLD | Structure of inner kinetochore ccan-cenp-a complex | electron microscopy | Z | — | — |
| 6QLE | Structure of inner kinetochore ccan complex | electron microscopy | Z | — | — |
| 6QLF | Structure of inner kinetochore ccan complex with MASK1 | electron microscopy | Z | — | — |
| 8OVX | Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus | electron microscopy | Z | — | 6 (best 0.84) |
| 8OW1 | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | electron microscopy | Z, ZZ | — | 3 (best 0.77) |
| Q06162 | AlphaFold monomer V2.0 prediction for inner kinetochore subunit NKP2 (Q06162) | predicted | A | — | — |
Experiment against prediction
- 8OW1 chain Z against the predicted model Q06162: TM-score 0.54, RMSD 2.18 Å
- 8OW1 chain ZZ against the predicted model Q06162: TM-score 0.52, RMSD 2.42 Å
- 6QLE chain Z against the predicted model Q06162: TM-score 0.50, RMSD 2.41 Å
- 6QLD chain Z against the predicted model Q06162: TM-score 0.49, RMSD 2.17 Å
- 6QLD chain Z against the predicted model Q06162: TM-score 0.49, RMSD 2.17 Å
- 8OVX chain Z against the predicted model Q06162: TM-score 0.48, RMSD 1.73 Å
- 6NUW chain J against the predicted model Q06162: TM-score 0.48, RMSD 4.43 Å
- 6QLF chain Z against the predicted model Q06162: TM-score 0.48, RMSD 2.30 Å
Elsewhere
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