UniProt Q05785
Epsin-2 (Q05785)
Epsin-2 (UniProt Q05785): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q05785
- Protein
- Epsin-2
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
Structures
9 records of Q05785 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4GZC | Crystal structure of yeast Ent2 ENTH domain | x-ray diffraction | A | — | — |
| 4GZC | Crystal structure of yeast ENT2 enth domain | x-ray diffraction | A | — | — |
| 4GZD | Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q | x-ray diffraction | A | — | — |
| 4GZD | Crystal structure of yeast ENT2 enth domain triple mutant N112D,S114E, E118Q | x-ray diffraction | A | — | — |
| 5ON7 | The ENTH domain from epsin-2 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2) | x-ray diffraction | A, B | PIO, SO4 | — |
| 5ON7 | The enth domain from epsin-2 in complex with phosphatidylinositol 4,5- bisphosphate (PIP2) | x-ray diffraction | A, B | PIO, SO4 | — |
| 6ENR | The ENTH domain from epsin Ent2 | x-ray diffraction | A | — | — |
| 6ENR | The enth domain from epsin ENT2 | x-ray diffraction | A | — | — |
| Q05785 | AlphaFold monomer V2.0 prediction for epsin-2 (Q05785) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4GZC chain A against the predicted model Q05785: TM-score 0.99, RMSD 0.39 Å
- 4GZC chain A against the predicted model Q05785: TM-score 0.99, RMSD 0.39 Å
- 4GZD chain A against the predicted model Q05785: TM-score 0.99, RMSD 0.41 Å
- 4GZD chain A against the predicted model Q05785: TM-score 0.99, RMSD 0.41 Å
- 6ENR chain A against the predicted model Q05785: TM-score 0.97, RMSD 0.91 Å
- 6ENR chain A against the predicted model Q05785: TM-score 0.97, RMSD 0.91 Å
- 5ON7 chain B against the predicted model Q05785: TM-score 0.95, RMSD 1.20 Å
- 5ON7 chain B against the predicted model Q05785: TM-score 0.95, RMSD 1.20 Å
- 5ON7 chain A against the predicted model Q05785: TM-score 0.93, RMSD 1.81 Å
- 5ON7 chain A against the predicted model Q05785: TM-score 0.93, RMSD 1.81 Å
Elsewhere
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