UniProt Q05762
Bifunctional dihydrofolate reductase-thymidylate synthase 1 (Q05762)
Bifunctional dihydrofolate reductase-thymidylate synthase 1 (UniProt Q05762), EC 1.5.1.3, 2.1.1.45: 1 experimental structure and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q05762
- Protein
- Bifunctional dihydrofolate reductase-thymidylate synthase 1
- EC
- 1.5.1.3, 2.1.1.45
- Experimental structures
- 1
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
2 records of Q05762 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8DAE | Arabidopsis thaliana bifunctional dihydrofolate reductase-thymidylate synthase | x-ray diffraction | A | — | 5 (best 0.66) |
| Q05762 | AlphaFold monomer V2.0 prediction for bifunctional dihydrofolate reductase-thymidylate synthase 1… | predicted | A | — | — |
Experiment against prediction
- 8DAE chain A against the predicted model Q05762: TM-score 0.99, RMSD 0.82 Å
Elsewhere
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