UniProt Q05498
rRNA-processing protein FCF1 (Q05498)
rRNA-processing protein FCF1 (UniProt Q05498): 26 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q05498
- Protein
- rRNA-processing protein FCF1
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 18 · 10 records with a druggable one
Structures
27 records of Q05498 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5WLC | The complete structure of the small subunit processome | electron microscopy | SL | ZN | — |
| 5WYJ | Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) | electron microscopy | U4 | — | — |
| 5WYK | Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP) | electron microscopy | U4 | — | — |
| 6KE6 | 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome | electron microscopy | 5K | ZN | 1 (best 0.88) |
| 6LQP | Cryo-EM structure of 90S small subunit preribosomes in transition states (State A) | electron microscopy | 5K | ZN | — |
| 6LQQ | Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) | electron microscopy | 5K | ZN | — |
| 6LQR | Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) | electron microscopy | 5K | ZN | — |
| 6LQS | Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) | electron microscopy | 5K | ZN | — |
| 6LQT | Cryo-EM structure of 90S small subunit preribosomes in transition states (State E) | electron microscopy | 5K | ZN | — |
| 6LQU | Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) | electron microscopy | 5K | ZN | — |
| 6LQV | Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) | electron microscopy | 5K | ZN | — |
| 6ND4 | Conformational switches control early maturation of the eukaryotic small ribosomal subunit | electron microscopy | l | — | — |
| 6ND4 | Conformational switches control early maturation of the eukaryotic small ribosomal subunit | electron microscopy | l | — | — |
| 6ZQA | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state A (Poly-Ala) | electron microscopy | UX | ZN | 1 (best 0.84) |
| 6ZQB | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state B2 | electron microscopy | UX | ZN | 3 (best 0.88) |
| 6ZQC | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Pre-A1 | electron microscopy | UX | ZN, MG | 2 (best 0.87) |
| 6ZQD | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1 | electron microscopy | UX | ZN | 2 (best 0.87) |
| 6ZQE | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A (Poly-Ala) | electron microscopy | UX | ZN | 2 (best 0.85) |
| 6ZQG | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-C | electron microscopy | UX | ZN | — |
| 7AJT | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | electron microscopy | UX | ZN, MG | 2 (best 0.88) |
| 7AJU | Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) | electron microscopy | UX | ZN | 2 (best 0.87) |
| 7D4I | Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1… | electron microscopy | 5K | ZN | — |
| 7D5S | Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) | electron microscopy | 5K | ZN | — |
| 7D5T | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) | electron microscopy | 5K | ZN | — |
| 7D63 | Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) | electron microscopy | 5K | ZN | 1 (best 0.86) |
| 7SUK | Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted… | electron microscopy | SL | — | 2 (best 0.87) |
| Q05498 | AlphaFold monomer V2.0 prediction for rRNA-processing protein FCF1 (Q05498) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6ZQG chain UX against the predicted model Q05498: TM-score 0.97, RMSD 0.91 Å
- 7D4I chain 5K against the predicted model Q05498: TM-score 0.96, RMSD 1.07 Å
- 7D5T chain 5K against the predicted model Q05498: TM-score 0.96, RMSD 1.07 Å
- 5WYK chain U4 against the predicted model Q05498: TM-score 0.94, RMSD 1.26 Å
- 5WYJ chain U4 against the predicted model Q05498: TM-score 0.91, RMSD 1.46 Å
- 6LQS chain 5K against the predicted model Q05498: TM-score 0.90, RMSD 1.61 Å
- 6LQT chain 5K against the predicted model Q05498: TM-score 0.90, RMSD 1.61 Å
- 6ZQC chain UX against the predicted model Q05498: TM-score 0.88, RMSD 2.01 Å
- 5WLC chain SL against the predicted model Q05498: TM-score 0.87, RMSD 2.01 Å
- 6KE6 chain 5K against the predicted model Q05498: TM-score 0.87, RMSD 2.02 Å
Elsewhere
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