UniProt Q04781
E3 ubiquitin-protein ligase listerin (Q04781)
E3 ubiquitin-protein ligase listerin (UniProt Q04781), EC 2.3.2.27, 6.3.2.-: 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q04781
- Protein
- E3 ubiquitin-protein ligase listerin
- EC
- 2.3.2.27, 6.3.2.-
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 9 · 4 records with a druggable one
Structures
8 records of Q04781 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FG0 | Structure of the conserved yeast listerin (Ltn1) N-terminal domain, MONOCLINIC FORM | x-ray diffraction | A, B | K | — |
| 5FG0 | Structure of the conserved yeast listerin (LTN1) N-terminal domain, monoclinic form | x-ray diffraction | A, B | — | — |
| 5FG1 | Structure of the conserved yeast listerin (Ltn1) selenomethionine-substituted N-terminal domain… | x-ray diffraction | A | K | 6 (best 0.67) |
| 5FG1 | Structure of the conserved yeast listerin (LTN1) selenomethionine- substituted N-terminal domain… | x-ray diffraction | A | — | — |
| 8AAF | Yeast RQC complex in state G | electron microscopy | e | ZN | 1 (best 0.88) |
| 8AGW | Yeast RQC complex in state D | electron microscopy | e | ZN | 1 (best 0.88) |
| 8AGZ | Yeast RQC complex in state with the RING domain of Ltn1 in the OUT position | electron microscopy | e | ZN | 1 (best 0.86) |
| Q04781 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase listerin (Q04781) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5FG0 chain A against the predicted model Q04781: TM-score 0.97, RMSD 1.41 Å
- 5FG0 chain A against the predicted model Q04781: TM-score 0.97, RMSD 1.41 Å
- 5FG1 chain A against the predicted model Q04781: TM-score 0.97, RMSD 1.58 Å
- 5FG1 chain A against the predicted model Q04781: TM-score 0.97, RMSD 1.58 Å
- 8AGW chain e against the predicted model Q04781: TM-score 0.55, RMSD 3.39 Å
- 8AAF chain e against the predicted model Q04781: TM-score 0.55, RMSD 3.39 Å
- 8AGZ chain e against the predicted model Q04781: TM-score 0.54, RMSD 3.80 Å
Elsewhere
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