UniProt Q04660
Ribosome biogenesis protein ERB1 (Q04660)
Ribosome biogenesis protein ERB1 (UniProt Q04660): 18 experimental structures and 1 predicted model on GenesisL1, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q04660
- Protein
- Ribosome biogenesis protein ERB1
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 32 · 10 records with a druggable one
Structures
19 records of Q04660 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4U7A | The carboxy-terminal domain of Erb1 is a seven-bladed beta-propeller that binds RNA. | x-ray diffraction | A | — | — |
| 4U7A | The carboxy-terminal domain of ERB1 is a seven-bladed beta-propeller that binds RNA. | x-ray diffraction | A | — | — |
| 6CB1 | Yeast nucleolar pre-60S ribosomal subunit (state 3) | electron microscopy | s | — | 7 (best 0.83) |
| 6CB1 | Yeast nucleolar pre-60S ribosomal subunit (state 3) | electron microscopy | s | — | — |
| 6ELZ | State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | electron microscopy | m | — | 4 (best 0.88) |
| 6EM3 | State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | B | — | — |
| 6EM3 | State a architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | B | — | — |
| 6EM4 | State B architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | H | — | — |
| 6EM5 | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | m | — | 1 (best 0.71) |
| 6EM5 | State D architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | m | — | — |
| 7NAC | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | electron microscopy | m | — | — |
| 7OHP | Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut… | electron microscopy | m | — | 2 (best 0.86) |
| 7OHR | Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae | electron microscopy | m | — | 3 (best 0.89) |
| 7OHS | Nog1-TAP associated immature ribosomal particle population F from S. cerevisiae | electron microscopy | m | — | 3 (best 0.88) |
| 7R7A | State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model | electron microscopy | m | — | 4 (best 0.89) |
| 8E5T | Yeast co-transcriptional Noc1-Noc2 RNP assembly checkpoint intermediate | electron microscopy | s | — | 2 (best 0.80) |
| 8V83 | 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) | electron microscopy | m | — | 3 (best 0.87) |
| 8V84 | 60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) | electron microscopy | m | — | 3 (best 0.89) |
| Q04660 | AlphaFold monomer V2.0 prediction for ribosome biogenesis protein ERB1 (Q04660) | predicted | A | — | — |
Experiment against prediction
- 4U7A chain A against the predicted model Q04660: TM-score 1.00, RMSD 0.29 Å
- 4U7A chain A against the predicted model Q04660: TM-score 1.00, RMSD 0.29 Å
- 6CB1 chain s against the predicted model Q04660: TM-score 0.88, RMSD 3.15 Å
- 6CB1 chain s against the predicted model Q04660: TM-score 0.88, RMSD 3.15 Å
- 6CB1 chain s against the predicted model A6ZMA9: TM-score 0.88, RMSD 3.01 Å
- 6CB1 chain s against the predicted model A6ZMA9: TM-score 0.88, RMSD 3.01 Å
- 6ELZ chain m against the predicted model Q04660: TM-score 0.75, RMSD 2.84 Å
- 6EM5 chain m against the predicted model Q04660: TM-score 0.75, RMSD 2.84 Å
- 6EM5 chain m against the predicted model Q04660: TM-score 0.75, RMSD 2.84 Å
- 7OHR chain m against the predicted model Q04660: TM-score 0.74, RMSD 2.70 Å
Elsewhere
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