UniProt Q04207
Transcription factor p65 (Q04207)
Transcription factor p65 (UniProt Q04207): 36 experimental structures on GenesisL1, 2 ligands bound, 56 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q04207
- Protein
- Transcription factor p65
- Experimental structures
- 36
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 56 · 7 records with a druggable one
Structures
36 records of Q04207 in the MolNFT archive: 36 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BFT | Structure of nf-kb P50 homodimer bound to a kb site | x-ray diffraction | A, B | — | — |
| 1BFT | Structure of nf-kb P50 homodimer bound to a kb site | x-ray diffraction | A, B | — | — |
| 1IKN | IKAPPABALPHA/NF-kappab complex | x-ray diffraction | A | — | — |
| 1IKN | IKAPPABALPHA/NF-kappab complex | x-ray diffraction | A | — | — |
| 1K3Z | X-ray crystal structure of the IkBb/NF-kB p65 homodimer complex | x-ray diffraction | A, B | — | — |
| 1K3Z | X-ray crystal structure of the IKBB/NF-kb P65 homodimer complex | x-ray diffraction | A, B | — | — |
| 1LE5 | Crystal structure of a NF-kB heterodimer bound to an IFNb-kB | x-ray diffraction | A, E | — | — |
| 1LE5 | Crystal structure of a nf-kb heterodimer bound to an ifnb-kb | x-ray diffraction | A, E | — | — |
| 1LE9 | Crystal structure of a NF-kB heterodimer bound to the Ig/HIV-kB siti | x-ray diffraction | A, E | — | — |
| 1LE9 | Crystal structure of a nf-kb heterodimer bound to the IG/HIV-kb siti | x-ray diffraction | A, E | — | — |
| 1LEI | The kB DNA sequence from the HLV-LTR functions as an allosteric regulator of HIV transcription | x-ray diffraction | A | — | — |
| 1LEI | The kb DNA sequence from the hlv-ltr functions as an allosteric regulator of HIV transcription | x-ray diffraction | A | — | — |
| 1MY5 | NF-kappaB p65 subunit dimerization domain homodimer | x-ray diffraction | A, B | — | — |
| 1MY5 | Nf-kappab P65 subunit dimerization domain homodimer | x-ray diffraction | A, B | — | — |
| 1MY7 | NF-kappaB p65 subunit dimerization domain homodimer N202R mutation | x-ray diffraction | A, B | — | — |
| 1MY7 | Nf-kappab P65 subunit dimerization domain homodimer N202R mutation | x-ray diffraction | A, B | — | — |
| 1OY3 | Crystal structure of an IKBBETA/NF-kb P65 homodimer complex | x-ray diffraction | C, B | — | — |
| 1OY3 | Crystal structure of an IKBBETA/NF-kb P65 homodimer complex | x-ray diffraction | C, B | — | — |
| 1RAM | A novel DNA recognition mode by nf-kb P65 homodimer | x-ray diffraction | A, B | — | — |
| 1RAM | A novel DNA recognition mode by nf-kb P65 homodimer | x-ray diffraction | A, B | — | — |
| 1VKX | Crystal structure of the nfkb P50/P65 heterodimer complexed to the immunoglobulin kb DNA | x-ray diffraction | A | — | — |
| 1VKX | Crystal structure of the nfkb P50/P65 heterodimer complexed to the immunoglobulin kb DNA | x-ray diffraction | A | — | — |
| 2I9T | Structure of NF-kB p65-p50 heterodimer bound to PRDII element of B-interferon promoter | x-ray diffraction | A | — | — |
| 2I9T | Structure of nf-kb P65-P50 heterodimer bound to prdii element of B- interferon promoter | x-ray diffraction | A | — | — |
| 2RAM | A novel DNA recognition mode by nf-kb P65 homodimer | x-ray diffraction | A, B | — | — |
| 2RAM | A novel DNA recognition mode by nf-kb P65 homodimer | x-ray diffraction | A, B | — | — |
| 5U01 | Cooperative DNA binding by two RelA dimers | x-ray diffraction | A, B, C, D | — | 10 (best 0.85) |
| 5U01 | Cooperative DNA binding by two rela dimers | x-ray diffraction | A, B, C, D | — | — |
| 6GGR | Crystal structure of Salmonella zinc metalloprotease effector GtgA in complex with p65 | x-ray diffraction | A | CL | 4 (best 0.70) |
| 6GGR | Crystal structure of salmonella zinc metalloprotease effector gtga in complex with P65 | x-ray diffraction | A | CL | — |
| 8U9L | Crystal Structure of RelA-cRel chimera complex with DNA | x-ray diffraction | A, B, G, H, K, L, O, P | — | 20 (best 0.86) |
| 9BDU | NF-kappaB RelA homo-dimer bound to AT-centric kappaB DNA | x-ray diffraction | A, B | SO4 | 6 (best 0.84) |
| 9BDV | NF-kappaB RelA homo-dimer bound to TA-centric kappaB DNA | x-ray diffraction | A, B | SO4 | 7 (best 0.82) |
| 9BDW | NF-kappaB RelA homo-dimer bound to GC-centric kappaB DNA | x-ray diffraction | A, B | SO4 | 4 (best 0.85) |
| 9BDX | NF-kappaB RelA homo-dimer bound to CG-centric kappaB DNA | x-ray diffraction | A, B | — | 5 (best 0.83) |
| Q04207 | AlphaFold monomer V2.0 prediction for transcription factor P65 (Q04207) | — | — | — |
Ligands
Experiment against prediction
- 8U9L chain G against the predicted model P15307: TM-score 0.97, RMSD 1.04 Å
- 8U9L chain A against the predicted model P15307: TM-score 0.97, RMSD 1.04 Å
- 8U9L chain K against the predicted model P15307: TM-score 0.97, RMSD 1.05 Å
- 8U9L chain O against the predicted model P15307: TM-score 0.97, RMSD 1.08 Å
- 8U9L chain H against the predicted model P15307: TM-score 0.97, RMSD 1.15 Å
- 8U9L chain B against the predicted model P15307: TM-score 0.97, RMSD 1.15 Å
- 8U9L chain P against the predicted model P15307: TM-score 0.97, RMSD 1.17 Å
- 8U9L chain L against the predicted model P15307: TM-score 0.97, RMSD 1.17 Å
Elsewhere
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