UniProt Q04178
Hypoxanthine-guanine phosphoribosyltransferase (Q04178)
Hypoxanthine-guanine phosphoribosyltransferase (UniProt Q04178): 6 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q04178
- Protein
- Hypoxanthine-guanine phosphoribosyltransferase
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
7 records of Q04178 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JKY | Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with gmp… | x-ray diffraction | A, B | — | — |
| 2JKY | Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with gmp… | x-ray diffraction | A, B | — | — |
| 2JKZ | Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with gmp… | x-ray diffraction | A, B, C, D | — | — |
| 2JKZ | Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with gmp… | x-ray diffraction | A, B, C, D | — | — |
| 2XBU | Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with GMP… | x-ray diffraction | A, B | — | — |
| 2XBU | Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with gmp… | x-ray diffraction | A, B | — | — |
| Q04178 | AlphaFold monomer V2.0 prediction for hypoxanthine-guanine phosphoribosyltransferase (Q04178) | predicted | A | — | 1 (best 0.29) |
Experiment against prediction
- 2JKZ chain A against the predicted model Q04178: TM-score 0.99, RMSD 0.64 Å
- 2JKZ chain A against the predicted model Q04178: TM-score 0.99, RMSD 0.64 Å
- 2XBU chain A against the predicted model Q04178: TM-score 0.99, RMSD 0.65 Å
- 2XBU chain A against the predicted model Q04178: TM-score 0.99, RMSD 0.65 Å
- 2XBU chain B against the predicted model Q04178: TM-score 0.98, RMSD 0.74 Å
- 2XBU chain B against the predicted model Q04178: TM-score 0.98, RMSD 0.74 Å
- 2JKY chain B against the predicted model Q04178: TM-score 0.98, RMSD 0.94 Å
- 2JKY chain B against the predicted model Q04178: TM-score 0.98, RMSD 0.94 Å
- 2JKY chain A against the predicted model Q04178: TM-score 0.87, RMSD 1.92 Å
- 2JKY chain A against the predicted model Q04178: TM-score 0.87, RMSD 1.92 Å
Elsewhere
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