UniProt Q03933
Heat shock factor protein 2 (Q03933)
Heat shock factor protein 2 (UniProt Q03933): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q03933
- Protein
- Heat shock factor protein 2
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 1 · 0 records with a druggable one
Structures
9 records of Q03933 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5D8K | Human HSF2 DNA-Binding Domain bound to 2-site HSE DNA at 1.73 Angstroms Resolution | x-ray diffraction | B | — | — |
| 5D8K | Human HSF2 DNA-binding domain bound to 2-site hse DNA at 1.73 ångströms resolution | x-ray diffraction | B | — | — |
| 5D8L | Human HSF2 DNA binding domain in complex with 3-site hse DNA at 2.1 ångströms resolution | x-ray diffraction | B, D, F, H | — | — |
| 5HDK | Crystal structure of heat shock factor 2-DBD | x-ray diffraction | A, B, C, D | K, NA, CL | — |
| 5HDK | Crystal structure of heat shock factor 2-dbd | x-ray diffraction | A, B, C, D | — | — |
| 7DCI | Crystal structure of HSF2 DNA-binding domain in complex with 2-site HSE DNA in the head-to-head… | x-ray diffraction | A | NA | 1 (best 0.44) |
| 7DCI | Crystal structure of HSF2 DNA-binding domain in complex with 2-site hse DNA in the head-to-head… | x-ray diffraction | A | NA | — |
| 7DCU | Crystal structure of HSF2 DNA-binding domain in complex with 3-site hse DNA (21 bp) | x-ray diffraction | A, B, C | NA | — |
| Q03933 | AlphaFold monomer V2.0 prediction for heat shock factor protein 2 (Q03933) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7DCU chain C against the predicted model Q03933: TM-score 0.99, RMSD 0.40 Å
- 7DCI chain A against the predicted model Q03933: TM-score 0.98, RMSD 0.52 Å
- 7DCI chain A against the predicted model Q03933: TM-score 0.98, RMSD 0.52 Å
- 5D8L chain D against the predicted model Q03933: TM-score 0.98, RMSD 0.60 Å
- 5D8L chain F against the predicted model Q03933: TM-score 0.97, RMSD 0.62 Å
- 5HDK chain C against the predicted model Q03933: TM-score 0.97, RMSD 0.64 Å
- 5HDK chain C against the predicted model Q03933: TM-score 0.97, RMSD 0.64 Å
- 5HDK chain B against the predicted model Q03933: TM-score 0.95, RMSD 1.02 Å
- 5HDK chain B against the predicted model Q03933: TM-score 0.95, RMSD 1.02 Å
- 5D8L chain B against the predicted model Q03933: TM-score 0.95, RMSD 1.14 Å
Elsewhere
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