UniProt Q03661
Silent chromatin protein ESC1 (Q03661)
Silent chromatin protein ESC1 (UniProt Q03661): 2 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q03661
- Protein
- Silent chromatin protein ESC1
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
3 records of Q03661 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6QSZ | Crystal structure of the Sir4 H-BRCT domain in complex with Esc1 pS1450 peptide | x-ray diffraction | B, D, F, H, J, L, N, P | — | 7 (best 0.69) |
| 6QSZ | Crystal structure of the SIR4 H-brct domain in complex with ESC1 PS1450 peptide | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| Q03661 | AlphaFold monomer V2.0 prediction for silent chromatin protein ESC1 (Q03661) | predicted | A | — | — |
Experiment against prediction
- 6QSZ chain D against the predicted model Q03661: TM-score 0.39, RMSD 0.61 Å
- 6QSZ chain D against the predicted model Q03661: TM-score 0.39, RMSD 0.61 Å
- 6QSZ chain N against the predicted model Q03661: TM-score 0.35, RMSD 1.15 Å
- 6QSZ chain N against the predicted model Q03661: TM-score 0.35, RMSD 1.15 Å
- 6QSZ chain J against the predicted model Q03661: TM-score 0.34, RMSD 1.87 Å
- 6QSZ chain J against the predicted model Q03661: TM-score 0.34, RMSD 1.87 Å
- 6QSZ chain P against the predicted model Q03661: TM-score 0.32, RMSD 1.44 Å
- 6QSZ chain P against the predicted model Q03661: TM-score 0.32, RMSD 1.44 Å
- 6QSZ chain H against the predicted model Q03661: TM-score 0.32, RMSD 2.90 Å
- 6QSZ chain H against the predicted model Q03661: TM-score 0.32, RMSD 2.90 Å
Elsewhere
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