UniProt Q03611
Cyclic nucleotide-gated cation channel (Q03611)
Cyclic nucleotide-gated cation channel (UniProt Q03611): 13 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 100 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q03611
- Protein
- Cyclic nucleotide-gated cation channel
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 100 · 5 records with a druggable one
Structures
14 records of Q03611 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5H3O | Structure of a eukaryotic cyclic nucleotide-gated channel | electron microscopy | A, B, C, D | PCG, NA | 20 (best 0.81) |
| 5H3O | Structure of a eukaryotic cyclic nucleotide-gated channel | electron microscopy | A, B, C, D | — | — |
| 6WEJ | Structure of cGMP-unbound WT TAX-4 reconstituted in lipid nanodiscs | electron microscopy | A, B, C, D | CPL, PX2, NA | 20 (best 0.76) |
| 6WEJ | Structure of cgmp-unbound wt tax-4 reconstituted in lipid nanodiscs | electron microscopy | A, B, C, D | CPL, PX2, NA | — |
| 6WEK | Structure of cgmp-bound wt tax-4 reconstituted in lipid nanodiscs | electron microscopy | A, B, C, D | PCG, CPL, PX2 | — |
| 6WEL | Structure of cGMP-unbound F403V/V407A mutant TAX-4 reconstituted in lipid nanodiscs | electron microscopy | A, B, C, D | CPL, PX2, NA | 20 (best 0.84) |
| 6WEL | Structure of cgmp-unbound F403V/V407A mutant tax-4 reconstituted in lipid nanodiscs | electron microscopy | A, B, C, D | CPL, PX2, NA | — |
| 7N15 | Structure of TAX-4_R421W w/cGMP open state | electron microscopy | A, B, C, D | PCG, CPL, PX2 | — |
| 7N15 | Structure of tax-4_R421W W/CGMP open state | electron microscopy | A, B, C, D | PCG, CPL, PX2 | — |
| 7N16 | Structure of TAX-4_R421W apo closed state | electron microscopy | D, A, B, C | CPL, NA | 20 (best 0.74) |
| 7N16 | Structure of tax-4_R421W apo closed state | electron microscopy | D, A, B, C | CPL, NA | — |
| 7N17 | Structure of TAX-4_R421W apo open state | electron microscopy | A, B, C, D | CPL | 20 (best 0.81) |
| 7N17 | Structure of tax-4_R421W apo open state | electron microscopy | A, B, C, D | CPL | — |
| Q03611 | AlphaFold monomer V2.0 prediction for cyclic nucleotide-gated cation channel (Q03611) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6WEJ chain B against the predicted model Q03611: TM-score 0.97, RMSD 1.52 Å
- 6WEJ chain B against the predicted model Q03611: TM-score 0.97, RMSD 1.52 Å
- 6WEJ chain D against the predicted model Q03611: TM-score 0.97, RMSD 1.52 Å
- 6WEJ chain D against the predicted model Q03611: TM-score 0.97, RMSD 1.52 Å
- 6WEJ chain C against the predicted model Q03611: TM-score 0.97, RMSD 1.52 Å
- 6WEJ chain C against the predicted model Q03611: TM-score 0.97, RMSD 1.52 Å
- 6WEJ chain A against the predicted model Q03611: TM-score 0.97, RMSD 1.52 Å
- 6WEJ chain A against the predicted model Q03611: TM-score 0.97, RMSD 1.52 Å
- 6WEL chain A against the predicted model Q03611: TM-score 0.97, RMSD 1.54 Å
- 6WEL chain A against the predicted model Q03611: TM-score 0.97, RMSD 1.54 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.