UniProt Q03468
DNA excision repair protein ERCC-6 (Q03468)
DNA excision repair protein ERCC-6 (UniProt Q03468), EC 3.6.4.-: 11 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q03468
- Protein
- DNA excision repair protein ERCC-6
- EC
- 3.6.4.-
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 10 · 4 records with a druggable one
Structures
12 records of Q03468 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4CVO | Crystal structure of the N-terminal colied-coil domain of human DNA excision repair protein ERCC-6 | x-ray diffraction | A | — | — |
| 4CVO | Crystal structure of the N-terminal colied-coil domain of human DNA excision repair protein ercc-6 | x-ray diffraction | A | — | — |
| 7OO3 | Pol II-CSB-CSA-DDB1-UVSSA (Structure1) | electron microscopy | b | — | 3 (best 0.82) |
| 7OO3 | Pol II-csb-csa-DDB1-uvssa (STRUCTURE1) | electron microscopy | b | — | — |
| 7OOB | Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) | electron microscopy | b | ADP, BEF, MG | 1 (best 0.85) |
| 7OOB | Pol II-csb-csa-DDB1-uvssa-ADPBEF3 (STRUCTURE2) | electron microscopy | b | ADP, BEF, MG | — |
| 7OOP | Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | electron microscopy | b | — | 3 (best 0.84) |
| 7OOP | Pol II-csb-csa-DDB1-uvssa-paf-SPT6 (structure 3) | electron microscopy | b | — | — |
| 7OPC | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 4) | electron microscopy | b | — | — |
| 7OPD | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 5) | electron microscopy | b | — | — |
| 9FD2 | Structure of Pol II-TC-NER-STK19 complex | electron microscopy | e | — | 3 (best 0.86) |
| Q03468 | AlphaFold monomer V2.0 prediction for DNA excision repair protein ercc-6 (Q03468) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7OPD chain b against the predicted model Q03468: TM-score 0.93, RMSD 1.49 Å
- 7OPC chain b against the predicted model Q03468: TM-score 0.93, RMSD 1.49 Å
- 7OOP chain b against the predicted model Q03468: TM-score 0.93, RMSD 1.66 Å
- 7OOP chain b against the predicted model Q03468: TM-score 0.93, RMSD 1.66 Å
- 7OO3 chain b against the predicted model Q03468: TM-score 0.93, RMSD 1.67 Å
- 7OO3 chain b against the predicted model Q03468: TM-score 0.93, RMSD 1.67 Å
- 7OOB chain b against the predicted model Q03468: TM-score 0.93, RMSD 1.64 Å
- 7OOB chain b against the predicted model Q03468: TM-score 0.93, RMSD 1.64 Å
- 9FD2 chain e against the predicted model Q03468: TM-score 0.92, RMSD 1.77 Å
- 4CVO chain A against the predicted model Q03468: TM-score 0.70, RMSD 1.39 Å
Elsewhere
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