UniProt Q03338
U4/U6 small nuclear ribonucleoprotein PRP3 (Q03338)
U4/U6 small nuclear ribonucleoprotein PRP3 (UniProt Q03338): 15 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q03338
- Protein
- U4/U6 small nuclear ribonucleoprotein PRP3
- Experimental structures
- 15
- Predicted models
- 1
- Pockets
- 10 · 3 records with a druggable one
Structures
16 records of Q03338 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCM | Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP | electron microscopy | K | — | — |
| 3JCM | Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snrnp | electron microscopy | K | — | — |
| 4YHU | Yeast Prp3 C-terminal fragment 296-469 | x-ray diffraction | A, B, C | — | — |
| 4YHU | Yeast PRP3 C-terminal fragment 296-469 | x-ray diffraction | A, B, C | — | — |
| 4YHV | Yeast Prp3 C-terminal fragment 325-469 | x-ray diffraction | A | — | — |
| 4YHV | Yeast PRP3 C-terminal fragment 325-469 | x-ray diffraction | A | — | — |
| 4YHW | Yeast Prp3 (296-469) in complex with fragment of U4/U6 di-snRNA | x-ray diffraction | A, B | — | — |
| 4YHW | Yeast PRP3 (296-469) in complex with fragment of U4/U6 di-snrna | x-ray diffraction | A, B | — | — |
| 5GAN | The overall structure of the yeast spliceosomal U4/U6.U5 tri-snrnp at 3.7 ångström | electron microscopy | G | — | — |
| 5GAP | Body region of the U4/U6.U5 tri-snRNP | electron microscopy | G | — | 4 (best 0.80) |
| 5GAP | Body region of the U4/U6.U5 tri-snrnp | electron microscopy | G | — | — |
| 5NRL | Structure of a pre-catalytic spliceosome | electron microscopy | G | — | 1 (best 0.81) |
| 5ZWM | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom… | electron microscopy | J | — | 1 (best 0.84) |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | electron microscopy | J | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström | electron microscopy | J | — | — |
| Q03338 | AlphaFold monomer V2.0 prediction for U4/U6 small nuclear ribonucleoprotein PRP3 (Q03338) | predicted | A | — | 4 (best 0.33) |
Experiment against prediction
- 4YHU chain B against the predicted model Q03338: TM-score 0.99, RMSD 0.45 Å
- 4YHU chain B against the predicted model Q03338: TM-score 0.99, RMSD 0.45 Å
- 4YHU chain C against the predicted model Q03338: TM-score 0.98, RMSD 0.55 Å
- 4YHU chain C against the predicted model Q03338: TM-score 0.98, RMSD 0.55 Å
- 4YHV chain A against the predicted model Q03338: TM-score 0.98, RMSD 0.90 Å
- 4YHV chain A against the predicted model Q03338: TM-score 0.98, RMSD 0.90 Å
- 4YHU chain A against the predicted model Q03338: TM-score 0.98, RMSD 0.75 Å
- 4YHU chain A against the predicted model Q03338: TM-score 0.98, RMSD 0.75 Å
- 4YHW chain A against the predicted model Q03338: TM-score 0.97, RMSD 0.86 Å
- 4YHW chain A against the predicted model Q03338: TM-score 0.97, RMSD 0.86 Å
Elsewhere
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