UniProt Q03188
Centromere protein C (Q03188)
Centromere protein C (UniProt Q03188): 26 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q03188
- Protein
- Centromere protein C
- Experimental structures
- 26
- Predicted models
- 1
- Pockets
- 22 · 9 records with a druggable one
Structures
27 records of Q03188 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LSJ | CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C delta-HEAD2 COMPLEX | x-ray diffraction | P, Q | — | 2 (best 0.55) |
| 5LSJ | Crystal structure of the human kinetochore MIS12-cenp-C delta-HEAD2 complex | x-ray diffraction | P, Q | — | — |
| 5LSK | Crystal structure of the human kinetochore MIS12-cenp-C complex | x-ray diffraction | P | — | 2 (best 0.67) |
| 5LSK | Crystal structure of the human kinetochore MIS12-cenp-C complex | x-ray diffraction | P | — | — |
| 6MUO | CENP-A nucleosome bound by two copies of CENP-C(CD) and one copy CENP-N(NT) | electron microscopy | K, L | — | 4 (best 0.86) |
| 6MUO | Cenp-a nucleosome bound by two copies of cenp-C(CD) and one copy cenp- N(NT) | electron microscopy | K, L | — | — |
| 6MUP | CENP-A nucleosome bound by two copies of CENP-C(CD) and two copies CENP-N(NT) | electron microscopy | K, L | — | 3 (best 0.82) |
| 6MUP | Cenp-a nucleosome bound by two copies of cenp-C(CD) and two copies cenp-N(NT) | electron microscopy | K, L | — | — |
| 6SE6 | Class2 : CENP-A nucleosome in complex with CENP-C central region | electron microscopy | V | — | — |
| 6SE6 | CLASS2 : cenp-a nucleosome in complex with cenp-C central region | electron microscopy | V | — | — |
| 6SEE | Class2A : CENP-A nucleosome in complex with CENP-C central region | electron microscopy | V | — | 2 (best 0.82) |
| 6SEE | CLASS2A : cenp-a nucleosome in complex with cenp-C central region | electron microscopy | V | — | — |
| 6SEF | Class2C : CENP-A nucleosome in complex with CENP-C central region | electron microscopy | V | — | 2 (best 0.81) |
| 6SEF | CLASS2C : cenp-a nucleosome in complex with cenp-C central region | electron microscopy | V | — | — |
| 7PII | Structure of the human CCAN CENP-A alpha-satellite complex | electron microscopy | K, L | — | 3 (best 0.82) |
| 7PII | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | K, L | — | — |
| 7QOO | Structure of the human inner kinetochore CCAN complex | electron microscopy | C | — | — |
| 7QOO | Structure of the human inner kinetochore ccan complex | electron microscopy | C | — | — |
| 7R5R | Structure of the human CCAN CENP-A alpha-satellite complex | electron microscopy | K, L | — | 2 (best 0.79) |
| 7R5R | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | K, L | — | — |
| 7XHN | Structure of human inner kinetochore CCAN-DNA complex | electron microscopy | C, c | — | — |
| 7XHO | Structure of human inner kinetochore CCAN complex | electron microscopy | C, c | — | — |
| 7YWX | Structure of the human CCAN CENP-A alpha-satellite complex | electron microscopy | a, b | — | — |
| 7YWX | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | a, b | — | — |
| 7YYH | Structure of the human CCANdeltaT CENP-A alpha-satellite complex | electron microscopy | k, l | — | 2 (best 0.83) |
| 7YYH | Structure of the human ccandeltat cenp-a alpha-satellite complex | electron microscopy | k, l | — | — |
| Q03188 | AlphaFold monomer V2.0 prediction for centromere protein C (Q03188) | predicted | A | — | — |
Experiment against prediction
- 7QOO chain C against the predicted model Q03188: TM-score 0.99, RMSD 0.05 Å
- 7QOO chain C against the predicted model Q03188: TM-score 0.99, RMSD 0.05 Å
- 7XHN chain C against the predicted model Q03188: TM-score 0.53, RMSD 0.51 Å
- 7XHO chain C against the predicted model Q03188: TM-score 0.44, RMSD 0.76 Å
- 7XHO chain c against the predicted model Q03188: TM-score 0.44, RMSD 1.68 Å
- 7XHN chain c against the predicted model Q03188: TM-score 0.43, RMSD 1.08 Å
- 5LSK chain P against the predicted model Q03188: TM-score 0.33, RMSD 2.79 Å
- 5LSK chain P against the predicted model Q03188: TM-score 0.33, RMSD 2.79 Å
- 6SE6 chain V against the predicted model Q03188: TM-score 0.29, RMSD 1.96 Å
- 6SE6 chain V against the predicted model Q03188: TM-score 0.29, RMSD 1.96 Å
Elsewhere
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