UniProt Q03132
6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Lsd14 Polyketide synthase fusion (Q03132)
6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Lsd14 Polyketide synthase fusion (UniProt Q03132), EC 2.3.1.94: 13 experimental structures on GenesisL1, 4 ligands bound, 48 pockets. Binding sites, pockets, druggability…
- UniProt
- Q03132
- Protein
- 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Lsd14 Polyketide…
- EC
- 2.3.1.94
- Experimental structures
- 13
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 48 · 3 records with a druggable one
Structures
13 records of Q03132 in the MolNFT archive: 13 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PZQ | Structure of fused docking domains from the erythromycin polyketide synthase (DEBS), a model for… | solution nmr | A, B | — | — |
| 1PZQ | Structure of fused docking domains from the erythromycin polyketide synthase (debs), a model for… | solution nmr | A, B | — | — |
| 1PZR | Structure of fused docking domains from the erythromycin polyketide synthase (DEBS), a model for… | solution nmr | A, B | — | — |
| 1PZR | Structure of fused docking domains from the erythromycin polyketide synthase (debs), a model for… | solution nmr | A, B | — | — |
| 3EL6 | Crystal Structure of the Erythromycin Dehydratase | x-ray diffraction | A | — | — |
| 3EL6 | Crystal structure of the erythromycin dehydratase | x-ray diffraction | A | — | — |
| 6C9U | Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex… | x-ray diffraction | A | K, NA | 12 (best 0.65) |
| 6C9U | Crystal structure of [KS3][AT3] didomain from module 3 of 6- deoxyerthronolide B synthase in… | x-ray diffraction | A | K, NA | — |
| 7M7E | 6-Deoxyerythronolide B synthase (DEBS) hybrid module (M3/1) in complex with antibody fragment 1B2 | electron microscopy | B, A | — | 19 (best 0.86) |
| 7M7E | 6-deoxyerythronolide B synthase (debs) hybrid module (M3/1) in complex with antibody fragment 1B2 | electron microscopy | B, A | — | — |
| 7S6C | Cryoem structure of modular pks holo-LSD14 stalled at the condensation step and bound to antibody… | electron microscopy | A, B, C, D | ATR, PNS | — |
| 7S6D | CryoEM structure of modular PKS holo-Lsd14 bound to antibody fragment 1B2, composite structure | electron microscopy | C, A, B | ATR | 17 (best 0.81) |
| 7S6D | Cryoem structure of modular pks holo-LSD14 bound to antibody fragment 1B2, composite structure | electron microscopy | C, A, B | ATR | — |
Ligands
Elsewhere
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