UniProt Q02ML7

CRISPR-associated endonuclease Cas1 (Q02ML7)

CRISPR-associated endonuclease Cas1 (UniProt Q02ML7), EC 3.1.-.-: 3 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q02ML7
Protein: CRISPR-associated endonuclease Cas1
EC: 3.1.-.-
Experimental structures: 3
Predicted models: 1
Pockets: 12 · 1 record with a druggable one

Structures

4 records of Q02ML7 in the MolNFT archive: 3 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
3GOD	Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated antiviral…	x-ray diffraction	A, B, C, D	—	—
3GOD	Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated antiviral…	x-ray diffraction	A, B, C, D	—	—
8FLJ	Cas1-Cas2/3 integrase and IHF bound to CRISPR leader, repeat and foreign DNA	electron microscopy	A, B, C, D	—	12 (best 0.80)
Q02ML7	AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS1 (Q02ML7)	predicted	A	—	—

Experiment against prediction

8FLJ chain B against the predicted model Q02ML7: TM-score 0.97, RMSD 1.39 Å
8FLJ chain D against the predicted model Q02ML7: TM-score 0.97, RMSD 1.38 Å
3GOD chain B against the predicted model Q02ML7: TM-score 0.95, RMSD 1.72 Å
3GOD chain B against the predicted model Q02ML7: TM-score 0.95, RMSD 1.72 Å
3GOD chain A against the predicted model Q02ML7: TM-score 0.95, RMSD 1.62 Å
3GOD chain A against the predicted model Q02ML7: TM-score 0.95, RMSD 1.62 Å
3GOD chain C against the predicted model Q02ML7: TM-score 0.79, RMSD 3.40 Å
3GOD chain C against the predicted model Q02ML7: TM-score 0.79, RMSD 3.40 Å
3GOD chain D against the predicted model Q02ML7: TM-score 0.77, RMSD 3.35 Å
3GOD chain D against the predicted model Q02ML7: TM-score 0.77, RMSD 3.35 Å

Elsewhere

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