UniProt Q02790
Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed (Q02790)
Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed (UniProt Q02790): 22 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q02790
- Protein
- Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
23 records of Q02790 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1N1A | Crystal Structure of the N-terminal domain of human FKBP52 | x-ray diffraction | A, B | — | — |
| 1N1A | Crystal structure of the N-terminal domain of human FKBP52 | x-ray diffraction | A, B | — | — |
| 1P5Q | Crystal Structure of FKBP52 C-terminal Domain | x-ray diffraction | A, B, C | — | — |
| 1P5Q | Crystal structure of FKBP52 C-terminal domain | x-ray diffraction | A, B, C | — | — |
| 1Q1C | Crystal structure of N(1-260) of human FKBP52 | x-ray diffraction | A | — | — |
| 1Q1C | Crystal structure of N(1-260) of human FKBP52 | x-ray diffraction | A | — | — |
| 1QZ2 | Crystal Structure of FKBP52 C-terminal Domain complex with the C-terminal peptide MEEVD of Hsp90 | x-ray diffraction | A, B, C | — | — |
| 1QZ2 | Crystal structure of FKBP52 C-terminal domain complex with the C-terminal peptide meevd of HSP90 | x-ray diffraction | A, B, C | — | — |
| 4DRJ | o-crystal structure of the PPIase domain of FKBP52, Rapamycin and the FRB fragment of mTOR | x-ray diffraction | A | — | — |
| 4DRJ | O-crystal structure of the ppiase domain of FKBP52, rapamycin and the frb fragment of mtor | x-ray diffraction | A | — | — |
| 4LAV | Crystal Structure Analysis of FKBP52, Crystal Form II | x-ray diffraction | A, B | — | — |
| 4LAV | Crystal structure analysis of FKBP52, crystal form II | x-ray diffraction | A, B | — | — |
| 4LAW | Crystal Structure Analysis of FKBP52, Crystal Form III | x-ray diffraction | A, B | — | — |
| 4LAW | Crystal structure analysis of FKBP52, crystal form III | x-ray diffraction | A, B | — | — |
| 4LAX | Crystal Structure Analysis of FKBP52, Complex with FK506 | x-ray diffraction | A | — | — |
| 4LAX | Crystal structure analysis of FKBP52, complex with FK506 | x-ray diffraction | A | — | — |
| 4LAY | Crystal Structure Analysis of FKBP52, Complex with I63 | x-ray diffraction | A | — | — |
| 4LAY | Crystal structure analysis of FKBP52, complex with I63 | x-ray diffraction | A | — | — |
| 4TW8 | The Fk1-Fk2 domains of FKBP52 in complex with iFit-FL | x-ray diffraction | A, B | — | — |
| 4TW8 | The FK1-FK2 domains of FKBP52 in complex with ifit-fl | x-ray diffraction | A, B | — | — |
| 6RCY | Crystal structure of FK1 domain of FKBP52 in complex with a bio- inspired hybrid fluorescent ligand | x-ray diffraction | A | K0T | — |
| 8FFV | Cryo-EM structure of the GR-Hsp90-FKBP52 complex | electron microscopy | D | — | 5 (best 0.75) |
| Q02790 | AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase FKBP4 (Q02790) | predicted | A | — | — |
Ligands
- K0T · (2~{S})-5-carbamimidamido-2-[[(2~{S})-2-[[(2~{S})-1-[5-(dimethylamino)naphthalen-1-yl]sulfonylpiperidin-2-yl]carbonylamino]-4-phenyl-butanoyl]amino]pentanoic acid · in 1 record
Experiment against prediction
- 4DRJ chain A against the predicted model Q02790: TM-score 0.98, RMSD 0.72 Å
- 4DRJ chain A against the predicted model Q02790: TM-score 0.98, RMSD 0.72 Å
- 4TW8 chain A against the predicted model Q02790: TM-score 0.96, RMSD 1.14 Å
- 4TW8 chain A against the predicted model Q02790: TM-score 0.96, RMSD 1.14 Å
- 1N1A chain B against the predicted model Q02790: TM-score 0.94, RMSD 1.18 Å
- 1N1A chain B against the predicted model Q02790: TM-score 0.94, RMSD 1.18 Å
- 1Q1C chain A against the predicted model Q02790: TM-score 0.94, RMSD 1.50 Å
- 1Q1C chain A against the predicted model Q02790: TM-score 0.94, RMSD 1.50 Å
- 1N1A chain A against the predicted model Q02790: TM-score 0.93, RMSD 0.80 Å
- 1N1A chain A against the predicted model Q02790: TM-score 0.93, RMSD 0.80 Å
Elsewhere
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