UniProt Q02641
Voltage-dependent L-type calcium channel subunit beta-1 (Q02641)
Voltage-dependent L-type calcium channel subunit beta-1 (UniProt Q02641): 8 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02641
- Protein
- Voltage-dependent L-type calcium channel subunit beta-1
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 3 · 3 records with a druggable one
Structures
9 records of Q02641 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7VFS | Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, apo state | electron microscopy | D | — | 1 (best 0.78) |
| 7VFS | Human N-type voltage gated calcium channel CAV2.2-ALPHA2/DELTA1-BETA1 complex, apo state | electron microscopy | D | — | — |
| 7VFU | Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to ziconotide | electron microscopy | D | — | 1 (best 0.74) |
| 7VFU | Human N-type voltage gated calcium channel CAV2.2-ALPHA2/DELTA1-BETA1 complex, bound to ziconotide | electron microscopy | D | — | — |
| 7VFV | Human N-type voltage gated calcium channel CAV2.2-ALPHA2/DELTA1-BETA1 complex, bound to PD173212 | electron microscopy | D | — | — |
| 7VFW | Human N-type voltage gated calcium channel CAV2.2-ALPHA2/DELTA1-BETA1 complex, bound to… | electron microscopy | D | — | — |
| 7XLQ | Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the… | electron microscopy | B | — | 1 (best 0.75) |
| 7YG5 | Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the… | electron microscopy | B | — | — |
| Q02641 | AlphaFold monomer V2.0 prediction for voltage-dependent L-type calcium channel subunit beta-1… | predicted | A | — | — |
Experiment against prediction
- 7VFU chain D against the predicted model Q02641: TM-score 0.99, RMSD 0.58 Å
- 7VFU chain D against the predicted model Q02641: TM-score 0.99, RMSD 0.58 Å
- 7VFS chain D against the predicted model Q02641: TM-score 0.98, RMSD 0.69 Å
- 7VFS chain D against the predicted model Q02641: TM-score 0.98, RMSD 0.69 Å
- 7VFV chain D against the predicted model Q02641: TM-score 0.97, RMSD 0.81 Å
- 7VFW chain D against the predicted model Q02641: TM-score 0.97, RMSD 0.81 Å
- 7XLQ chain B against the predicted model Q02641: TM-score 0.97, RMSD 0.83 Å
- 7YG5 chain B against the predicted model Q02641: TM-score 0.96, RMSD 0.97 Å
Elsewhere
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