UniProt Q02224
Centromere-associated protein E (Q02224)
Centromere-associated protein E (UniProt Q02224): 8 experimental structures on GenesisL1, 5 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q02224
- Protein
- Centromere-associated protein E
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 15 · 3 records with a druggable one
Structures
8 records of Q02224 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1T5C | Crystal structure of the motor domain of human kinetochore protein CENP-E | x-ray diffraction | A, B | — | — |
| 1T5C | Crystal structure of the motor domain of human kinetochore protein cenp-E | x-ray diffraction | A, B | — | — |
| 5JVP | The neck-linker and alpha 7 helix of Homo sapiens CENP-E | x-ray diffraction | A, B, C, D, E, F | CD | — |
| 5JVP | The neck-linker and alpha 7 helix of homo sapiens cenp-E | x-ray diffraction | A, B, C, D, E, F | CD | 1 (best 0.38) |
| 6M4I | Structure of CENP-E motor domain at 1.9 angstrom resolution | x-ray diffraction | A, B | ADP, MG | 6 (best 0.58) |
| 6M4I | Structure of cenp-E motor domain at 1.9 ångström resolution | x-ray diffraction | A, B | ADP, MG | — |
| 8HFH | CENP-E motor domain in complex with AMPPNP and Mg2+ | x-ray diffraction | A | ANP, MG, NA | 3 (best 0.55) |
| 8WHL | Crystal structure of CLASP2 in complex with CENP-E | x-ray diffraction | F, H, G, E | — | 5 (best 0.74) |
Ligands
Experiment against prediction
- 5JVP chain B against the predicted model Q15691: TM-score 0.71, RMSD 2.14 Å
- 5JVP chain F against the predicted model Q15691: TM-score 0.71, RMSD 2.04 Å
- 5JVP chain A against the predicted model Q15691: TM-score 0.69, RMSD 2.33 Å
- 5JVP chain D against the predicted model Q15691: TM-score 0.68, RMSD 2.44 Å
Elsewhere
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