UniProt Q02199

Nucleoporin NUP49/NSP49 (Q02199)

Nucleoporin NUP49/NSP49 (UniProt Q02199): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q02199
Protein: Nucleoporin NUP49/NSP49
Experimental structures: 4
Predicted models: 1
Pockets: 3 · 1 record with a druggable one

Structures

5 records of Q02199 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7N85	Inner ring spoke from the isolated yeast NPC	electron microscopy	C, F, I, L	—	—
7N9F	Structure of the in situ yeast NPC	electron microscopy	C, F, I, L	—	—
7WOO	Cryo-EM structure of the inner ring protomer of the Saccharomyces cerevisiae nuclear pore complex	electron microscopy	G, J	—	3 (best 0.85)
7WOO	Cryo-EM structure of the inner ring protomer of the saccharomyces cerevisiae nuclear pore complex	electron microscopy	G, J	—	—
Q02199	AlphaFold monomer V2.0 prediction for nucleoporin NUP49/NSP49 (Q02199)	predicted	A	—	—

Experiment against prediction

7N85 chain L against the predicted model Q02199: TM-score 0.71, RMSD 3.25 Å
7WOO chain G against the predicted model Q02199: TM-score 0.68, RMSD 3.69 Å
7WOO chain G against the predicted model Q02199: TM-score 0.68, RMSD 3.69 Å
7WOO chain J against the predicted model Q02199: TM-score 0.68, RMSD 3.91 Å
7WOO chain J against the predicted model Q02199: TM-score 0.68, RMSD 3.91 Å
7N85 chain F against the predicted model Q02199: TM-score 0.66, RMSD 3.67 Å
7N9F chain L against the predicted model Q02199: TM-score 0.63, RMSD 3.88 Å
7N85 chain C against the predicted model Q02199: TM-score 0.61, RMSD 4.16 Å
7N85 chain I against the predicted model Q02199: TM-score 0.60, RMSD 4.12 Å
7N9F chain I against the predicted model Q02199: TM-score 0.59, RMSD 3.72 Å

Elsewhere

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