UniProt Q02053
Ubiquitin-activating enzyme E1 1 (Q02053)
Ubiquitin-activating enzyme E1 1 (UniProt Q02053): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 35 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02053
- Protein
- Ubiquitin-activating enzyme E1 1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 35 · 3 records with a druggable one
Structures
7 records of Q02053 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Z7L | Crystal structure of fragment of mouse ubiquitin-activating enzyme | x-ray diffraction | A, B, C | TBR | 12 (best 0.77) |
| 1Z7L | Crystal structure of fragment of mouse ubiquitin-activating enzyme | x-ray diffraction | A, B, C | TBR | 12 (best 0.77) |
| 2LZJ | Refined solution structure and dynamics of First Catalytic Cysteine Half-domain from mouse E1 enzyme | solution nmr | A | — | 1 (best 0.40) |
| 2LZJ | Refined solution structure and dynamics of first catalytic cysteine half-domain from mouse E1 enzyme | solution nmr | A | — | 1 (best 0.40) |
| 2V31 | Structure of First Catalytic Cysteine Half-domain of mouse ubiquitin- activating enzyme | solution nmr | A | — | — |
| 2V31 | Structure of first catalytic cysteine half-domain of mouse ubiquitin- activating enzyme | solution nmr | A | — | — |
| Q02053 | AlphaFold monomer V2.0 prediction for ubiquitin-like modifier- activating enzyme 1 (Q02053) | predicted | A | — | 9 (best 0.73) |
Ligands
- TBR · Hexatantalum dodecabromide · in 2 records
Experiment against prediction
- 1Z7L chain A against the predicted model Q02053: TM-score 0.98, RMSD 0.94 Å
- 1Z7L chain A against the predicted model Q02053: TM-score 0.98, RMSD 0.94 Å
- 2LZJ chain A against the predicted model Q02053: TM-score 0.73, RMSD 2.91 Å
- 2LZJ chain A against the predicted model Q02053: TM-score 0.73, RMSD 2.91 Å
- 2V31 chain A against the predicted model Q02053: TM-score 0.68, RMSD 1.96 Å
- 2V31 chain A against the predicted model Q02053: TM-score 0.68, RMSD 1.96 Å
Elsewhere
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