UniProt Q01543
Friend leukemia integration 1 transcription factor (Q01543)
Friend leukemia integration 1 transcription factor (UniProt Q01543): 17 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q01543
- Protein
- Friend leukemia integration 1 transcription factor
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 14 · 4 records with a druggable one
Structures
18 records of Q01543 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FLI | DNA-binding domain of fli-1 | solution nmr | A | — | — |
| 1FLI | DNA-binding domain of fli-1 | solution nmr | A | — | — |
| 1X66 | Solution structure of the SAM_PNT-domain of the human friend LEUKEMIAINTEGRATION 1 transcription… | solution nmr | A | — | — |
| 1X66 | Solution structure of the SAM_PNT-domain of the human friend leukemiaintegration 1 transcription… | solution nmr | A | — | — |
| 2YTU | Solution structure of the SAM_PNT-domain of the human friend LEUKEMIAINTEGRATION 1 transcription… | solution nmr | A | — | — |
| 2YTU | Solution structure of the SAM_PNT-domain of the human friend leukemiaintegration 1 transcription… | solution nmr | A | — | — |
| 5E8G | Crystal structure of the DNA binding domain of human transcription factor FLI1 | x-ray diffraction | A, B, C, D | CO | 1 (best 0.55) |
| 5E8G | Crystal structure of the DNA binding domain of human transcription factor FLI1 | x-ray diffraction | A, B, C, D | — | — |
| 5E8I | Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with a… | x-ray diffraction | A, D, G, J | — | — |
| 5E8I | Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with a… | x-ray diffraction | A, D, G, J | — | — |
| 5JVT | Crystal structure of the DNA binding domain of transcription factor FLI1 in complex with an 11-mer… | x-ray diffraction | A, D, G | PO4 | 4 (best 0.59) |
| 5JVT | Crystal structure of the DNA binding domain of transcription factor FLI1 in complex with an 11-mer… | x-ray diffraction | A, D, G | — | — |
| 6VG2 | Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with… | x-ray diffraction | A, D | — | 5 (best 0.51) |
| 6VG2 | Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with… | x-ray diffraction | A, D | — | — |
| 6VG8 | Crystal structure of the DNA binding domains of human FLI1 and RUNX2 in complex with 16-mer DNA… | x-ray diffraction | A | — | — |
| 6VGD | Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the DBD of human… | x-ray diffraction | A | — | 4 (best 0.61) |
| 6VGD | Crystal structure of the DNA binding domain (dbd) of human FLI1 and the complex of the dbd of human… | x-ray diffraction | A | — | — |
| Q01543 | AlphaFold monomer V2.0 prediction for friend leukemia integration 1 transcription factor (Q01543) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5JVT chain G against the predicted model Q01543: TM-score 0.99, RMSD 0.42 Å
- 5JVT chain G against the predicted model Q01543: TM-score 0.99, RMSD 0.42 Å
- 5JVT chain D against the predicted model Q01543: TM-score 0.98, RMSD 0.45 Å
- 5JVT chain D against the predicted model Q01543: TM-score 0.98, RMSD 0.45 Å
- 5E8I chain A against the predicted model Q01543: TM-score 0.98, RMSD 0.48 Å
- 5E8I chain A against the predicted model Q01543: TM-score 0.98, RMSD 0.48 Å
- 5E8I chain D against the predicted model Q01543: TM-score 0.98, RMSD 0.55 Å
- 5E8I chain D against the predicted model Q01543: TM-score 0.98, RMSD 0.55 Å
- 5E8I chain J against the predicted model Q01543: TM-score 0.98, RMSD 0.58 Å
- 5E8I chain J against the predicted model Q01543: TM-score 0.98, RMSD 0.58 Å
Elsewhere
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