UniProt Q01433
AMP deaminase 2 (Q01433)
AMP deaminase 2 (UniProt Q01433), EC 3.5.4.6: 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 40 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q01433
- Protein
- AMP deaminase 2
- EC
- 3.5.4.6
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 40 · 2 records with a druggable one
Structures
7 records of Q01433 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4NO3 | Crystal structure of AMPD2 phosphopeptide bound to HLA-A2 | x-ray diffraction | C | — | — |
| 4NO3 | Crystal structure of AMPD2 phosphopeptide bound to HLA-A2 | x-ray diffraction | C | — | — |
| 4NO5 | Crystal structure of non-phosphorylated form of AMPD2 phosphopeptide bound to HLA-A2 | x-ray diffraction | C | — | — |
| 4NO5 | Crystal structure of non-phosphorylated form of AMPD2 phosphopeptide bound to HLA-A2 | x-ray diffraction | C | — | — |
| 8HU6 | AMP deaminase 2 in complex with AMP | x-ray diffraction | A, B, C, D | ZN, SO4, AMP | 20 (best 0.81) |
| 8HUB | AMP deaminase 2 in complex with an inhibitor | x-ray diffraction | A, B, C, D | ZN, N4X | 20 (best 0.78) |
| Q01433 | AlphaFold monomer V2.0 prediction for AMP deaminase 2 (Q01433) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8HU6 chain B against the predicted model Q01433: TM-score 0.99, RMSD 0.84 Å
- 8HU6 chain A against the predicted model Q01433: TM-score 0.99, RMSD 0.83 Å
- 8HU6 chain C against the predicted model Q01433: TM-score 0.99, RMSD 0.93 Å
- 8HU6 chain D against the predicted model Q01433: TM-score 0.99, RMSD 1.10 Å
- 8HUB chain A against the predicted model Q01433: TM-score 0.98, RMSD 1.14 Å
- 8HUB chain B against the predicted model Q01433: TM-score 0.98, RMSD 1.68 Å
- 8HUB chain D against the predicted model Q01433: TM-score 0.97, RMSD 1.92 Å
- 8HUB chain C against the predicted model Q01433: TM-score 0.96, RMSD 2.11 Å
- 4NO5 chain C against the predicted model Q01433: TM-score 0.49, RMSD 0.63 Å
- 4NO5 chain C against the predicted model Q01433: TM-score 0.49, RMSD 0.63 Å
Elsewhere
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