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UniProt Q01225

Protein B2 (Q01225)

Protein B2 (UniProt Q01225): 5 experimental structures on GenesisL1, 3 ligands bound, 30 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q01225
Protein
Protein B2
Experimental structures
5
Predicted models
0
Ligands
3
Pockets
30 · 2 records with a druggable one

Structures

5 records of Q01225 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6EA6Structure of VACV poxin 2'3' cGAMP-specific nucleasex-ray diffractionA, C, B, D—10 (best 0.74)
6EA6Structure of vacv poxin 2'3' cgamp-specific nucleasex-ray diffractionA, C, B, D——
6EA8Structure of VACV poxin in pre-reactive state with nonhydrolyzable 2'3' cGAMPx-ray diffractionA, B, C, D, E, F, G, H, I, JJ2A, J2B20 (best 0.76)
6EA8Structure of vacv poxin in pre-reactive state with nonhydrolyzable 2'3' cgampx-ray diffractionA, B, C, D, E, F, G, H, I, JJ2A, J2B—
6EA9Structure of vacv poxin in post-reactive state with GP[2'-5']AP[3']x-ray diffractionA, B, C, D, E9BG—

Ligands

  • J2A · (2s,5r,7r,8r,10r,12ar,14r,15r,15as,16r)-7-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-15,16-dihydroxy-2,10-disulfanyloctahydro-2H,10H, 12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-L][1, 3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione · in 2 records
  • J2B · O-[(1R,2R,3R)-5-{[(S)-{[(2R,3R,4R,5R)-2-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl]oxy}(sulfanyl) phosphoryl]oxy}-1-(6-amino-9H-purin-9-yl)-1,2-dihydroxypentan-3-yl] dihydrogen (R)-phosphorothioate · in 2 records
  • 9BG · 2',5'-GpAp · in 1 record

Elsewhere

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