UniProt Q01094
Q01094
Q01094 (UniProt Q01094): 7 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q01094
- Experimental structures
- 7
- Predicted models
- 1
Structures
8 records of Q01094 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H24 | CDK2/CyclinA in complex with a 9 residue recruitment peptide from E2F | x-ray diffraction | E | — | — |
| 1H24 | CDK2/CYCLIN a in complex with a 9 residue recruitment peptide from E2F | x-ray diffraction | E | — | — |
| 1O9K | Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide | x-ray diffraction | P, Q, R, S | — | — |
| 1O9K | Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide | x-ray diffraction | P, Q, R, S | — | — |
| 2AZE | Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer | x-ray diffraction | B | — | — |
| 2AZE | Structure of the rb C-terminal domain bound to an E2F1-DP1 heterodimer | x-ray diffraction | B | — | — |
| 6G0P | Crystal structure of the first bromodomain of human BRD4 in complex with an acetylated E2F1 peptide… | x-ray diffraction | B | — | — |
| Q01094 | AlphaFold monomer V2.0 prediction for transcription factor E2F1 (Q01094) | predicted | A | — | — |
Experiment against prediction
- 2AZE chain B against the predicted model Q01094: TM-score 0.95, RMSD 0.97 Å
- 2AZE chain B against the predicted model Q01094: TM-score 0.95, RMSD 0.97 Å
- 6G0P chain B against the predicted model Q01094: TM-score 0.49, RMSD 1.30 Å
- 1H24 chain E against the predicted model Q01094: TM-score 0.39, RMSD 1.12 Å
- 1H24 chain E against the predicted model Q01094: TM-score 0.39, RMSD 1.12 Å
- 1O9K chain Q against the predicted model Q01094: TM-score 0.35, RMSD 1.12 Å
- 1O9K chain Q against the predicted model Q01094: TM-score 0.35, RMSD 1.12 Å
- 1O9K chain P against the predicted model Q01094: TM-score 0.35, RMSD 1.00 Å
- 1O9K chain P against the predicted model Q01094: TM-score 0.35, RMSD 1.00 Å
- 1O9K chain S against the predicted model Q01094: TM-score 0.35, RMSD 1.04 Å
Elsewhere
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