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UniProt Q00942

DNA topoisomerase 2 (Q00942)

DNA topoisomerase 2 (UniProt Q00942), EC 5.6.2.2: 3 experimental structures on GenesisL1, 4 ligands bound, 27 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q00942
Protein
DNA topoisomerase 2
EC
5.6.2.2
Experimental structures
3
Predicted models
0
Ligands
4
Pockets
27 · 3 records with a druggable one

Structures

3 records of Q00942 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8XRFThe crystal structure of AsfvTopII in complex with G-DNAx-ray diffractionA, BMG20 (best 0.81)
8XRGThe crystal structure of AsfvTopII ATPase domain in complex with ADPx-ray diffractionAADP, PO4, MG3 (best 0.76)
8XRHThe crystal structure of AsfvTopII ATPase domain in complex with AMPPNPx-ray diffractionAANP, MG4 (best 0.75)

Ligands

  • MG · Magnesium ion · in 3 records
  • ADP · Adenosine-5'-diphosphate · in 1 record
  • ANP · Phosphoaminophosphonic acid-adenylate ester · in 1 record
  • PO4 · Phosphate ion · in 1 record

Elsewhere

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