UniProt Q00688
Peptidyl-prolyl cis-trans isomerase FKBP3 (Q00688)
Peptidyl-prolyl cis-trans isomerase FKBP3 (UniProt Q00688), EC 5.2.1.8: 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q00688
- Protein
- Peptidyl-prolyl cis-trans isomerase FKBP3
- EC
- 5.2.1.8
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 2 · 1 record with a druggable one
Structures
11 records of Q00688 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PBK | Homologous domain of human FKBP25 | x-ray diffraction | A | — | — |
| 1PBK | Homologous domain of human FKBP25 | x-ray diffraction | A | — | — |
| 2KFV | Structure of the amino-terminal domain of human FK506-binding protein 3 / Northeast Structural… | solution nmr | A | — | — |
| 2KFV | Structure of the amino-terminal domain of human FK506-binding protein 3 / northeast structural… | solution nmr | A | — | — |
| 2MPH | Solution Structure of human FK506 binding Protein 25 | solution nmr | A | — | — |
| 2MPH | Solution structure of human FK506 binding protein 25 | solution nmr | A | — | — |
| 5D75 | Crystal structure of Human FKBD25 in complex with FK506 | x-ray diffraction | A | FK5, JEF | 1 (best 0.37) |
| 5D75 | Crystal structure of human FKBD25 in complex with FK506 | x-ray diffraction | A | — | — |
| 5GPG | Co-crystal structure of the FK506 binding domain of human FKBP25, Rapamycin and the FRB domain of… | x-ray diffraction | A | RAP | 1 (best 0.78) |
| 5GPG | Co-crystal structure of the FK506 binding domain of human FKBP25, rapamycin and the frb domain of… | x-ray diffraction | A | — | — |
| Q00688 | AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase FKBP3 (Q00688) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5GPG chain A against the predicted model Q00688: TM-score 0.99, RMSD 0.48 Å
- 5GPG chain A against the predicted model Q00688: TM-score 0.99, RMSD 0.48 Å
- 1PBK chain A against the predicted model Q00688: TM-score 0.96, RMSD 0.69 Å
- 1PBK chain A against the predicted model Q00688: TM-score 0.96, RMSD 0.69 Å
- 5D75 chain A against the predicted model Q00688: TM-score 0.94, RMSD 0.70 Å
- 5D75 chain A against the predicted model Q00688: TM-score 0.94, RMSD 0.70 Å
- 2KFV chain A against the predicted model Q00688: TM-score 0.90, RMSD 1.35 Å
- 2KFV chain A against the predicted model Q00688: TM-score 0.90, RMSD 1.35 Å
- 2MPH chain A against the predicted model Q00688: TM-score 0.50, RMSD 1.96 Å
- 2MPH chain A against the predicted model Q00688: TM-score 0.50, RMSD 1.96 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.