UniProt P9WQ35
Adenylate cyclase (P9WQ35)
Adenylate cyclase (UniProt P9WQ35), EC 4.6.1.1: 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WQ35
- Protein
- Adenylate cyclase
- EC
- 4.6.1.1
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 15 · 1 record with a druggable one
Structures
4 records of P9WQ35 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7YZ9 | Structure of catalytic domain of Rv1625c bound to nanobody NB4 | x-ray diffraction | A | MN, ONM | 1 (best 0.40) |
| 7YZ9 | Structure of catalytic domain of RV1625C bound to nanobody NB4 | x-ray diffraction | A | MN, ONM | — |
| 7YZI | Structure of Mycobacterium tuberculosis adenylyl cyclase Rv1625c / Cya | electron microscopy | A, B | ONM, MN | 14 (best 0.85) |
| P9WQ35 | AlphaFold monomer V2.0 prediction for adenylate cyclase (P9WQ35) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7YZ9 chain A against the predicted model P9WQ35: TM-score 0.94, RMSD 1.48 Å
- 7YZ9 chain A against the predicted model P9WQ35: TM-score 0.94, RMSD 1.48 Å
- 7YZI chain A against the predicted model P9WQ35: TM-score 0.92, RMSD 2.17 Å
- 7YZI chain B against the predicted model P9WQ35: TM-score 0.92, RMSD 2.17 Å
Elsewhere
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