UniProt P9WQ01
Acetylglutamate kinase (P9WQ01)
Acetylglutamate kinase (UniProt P9WQ01), EC 2.7.2.8: 24 experimental structures and 1 predicted model on GenesisL1, 15 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WQ01
- Protein
- Acetylglutamate kinase
- EC
- 2.7.2.8
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 15
- Pockets
- 15 · 7 records with a druggable one
Structures
25 records of P9WQ01 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7NLF | Crystal structure of mycobacterium tuberculosis argb in apo form. | x-ray diffraction | A | SO4 | — |
| 7NLN | Crystal structure of Mycobacterium tuberculosis ArgB in complex with N-acetyl-glutamate | x-ray diffraction | A, B | NLG | 7 (best 0.66) |
| 7NLN | Crystal structure of mycobacterium tuberculosis argb in complex with N-acetyl-glutamate | x-ray diffraction | A, B | NLG | — |
| 7NLO | Crystal structure of mycobacterium tuberculosis argb in complex with L-arginine | x-ray diffraction | A | — | — |
| 7NLP | Crystal structure of mycobacterium tuberculosis argb in complex with L-canavanine | x-ray diffraction | A | SO4 | — |
| 7NLQ | Crystal structure of mycobacterium tuberculosis argb in complex with 2-(isoxazol-5-YL)PHENOL | x-ray diffraction | A | 97T, SO4 | — |
| 7NLR | Crystal structure of Mycobacterium tuberculosis ArgB in complex with 2-phenyl-1H-imidazole | x-ray diffraction | A | SO4, PIY | 1 (best 0.64) |
| 7NLR | Crystal structure of mycobacterium tuberculosis argb in complex with 2-phenyl-1H-imidazole | x-ray diffraction | A | SO4, PIY | — |
| 7NLS | Crystal structure of mycobacterium tuberculosis argb in complex with methyl 4-hydroxy-3-iodobenzoate | x-ray diffraction | A | 98T, SO4 | — |
| 7NLT | Crystal structure of Mycobacterium tuberculosis ArgB in complex with… | x-ray diffraction | A | 14N, SO4 | 1 (best 0.61) |
| 7NLT | Crystal structure of mycobacterium tuberculosis argb in complex with… | x-ray diffraction | A | 14N, SO4 | — |
| 7NLU | Crystal structure of mycobacterium tuberculosis argb in complex with 1-(1H-indol-3-YL)ETHAN-1-one | x-ray diffraction | A | SO4, 5RN | — |
| 7NLW | Crystal structure of Mycobacterium tuberculosis ArgB in complex with… | x-ray diffraction | A | UOK, SO4 | 1 (best 0.60) |
| 7NLW | Crystal structure of mycobacterium tuberculosis argb in complex with… | x-ray diffraction | A | UOK, SO4 | — |
| 7NLX | Crystal structure of Mycobacterium tuberculosis ArgB in complex with… | x-ray diffraction | A | 97W, SO4 | 1 (best 0.58) |
| 7NLX | Crystal structure of mycobacterium tuberculosis argb in complex with… | x-ray diffraction | A | 97W, SO4 | — |
| 7NLY | Crystal structure of mycobacterium tuberculosis argb in complex with 2-chlorobenzimidazole. | x-ray diffraction | A | SO4, 98K | — |
| 7NLZ | Crystal structure of mycobacterium tuberculosis argb in complex with… | x-ray diffraction | A | 98Q, SO4 | — |
| 7NM0 | Crystal structure of Mycobacterium tuberculosis ArgB in complex with… | x-ray diffraction | A | 9EQ, SO4 | 2 (best 0.61) |
| 7NM0 | Crystal structure of mycobacterium tuberculosis argb in complex with… | x-ray diffraction | A | 9EQ, SO4 | — |
| 7NN7 | Crystal structure of Mycobacterium tuberculosis ArgB in complex with dimethyl 5-hydroxyisophthalate. | x-ray diffraction | A | 98W, SO4 | 2 (best 0.61) |
| 7NN7 | Crystal structure of mycobacterium tuberculosis argb in complex with dimethyl 5-hydroxyisophthalate. | x-ray diffraction | A | 98W, SO4 | — |
| 7NN8 | Crystal structure of mycobacterium tuberculosis argb in complex with 1H-indole-3-carbonitrile. | x-ray diffraction | A | SO4, 98Z | — |
| 7NNB | Crystal structure of mycobacterium tuberculosis argb in complex with… | x-ray diffraction | A | 97Q, SO4 | — |
| P9WQ01 | AlphaFold monomer V2.0 prediction for acetylglutamate kinase (P9WQ01) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 21 records
- 14N · 4-(4-methylpiperazin-1-yl)benzoic acid · in 2 records
- 97W · 7-(trifluoromethyl)quinolin-4-ol · in 2 records
- 98W · dimethyl 5-oxidanylbenzene-1,3-dicarboxylate · in 2 records
- 9EQ · 1-[2,6-bis(oxidanyl)phenyl]ethanone · in 2 records
- NLG · N-acetyl-L-glutamate · in 2 records
- PIY · 2-phenyl-1H-imidazole · in 2 records
- UOK · 2-(5-methoxy-1~{H}-indol-3-yl)ethanenitrile · in 2 records
- 5RN · 1-(1~{H}-indol-3-yl)ethanone · in 1 record
- 97Q · 2,8-bis(trifluoromethyl)quinolin-4-ol · in 1 record
- 97T · 2-(1,2-oxazol-5-yl)phenol · in 1 record
- 98K · 2-chloranyl-1~{H}-benzimidazole · in 1 record
- 98Q · 5-methoxy-6-(trifluoromethyl)-1~{H}-indole · in 1 record
- 98T · methyl 3-iodanyl-4-oxidanyl-benzoate · in 1 record
- 98Z · 1~{H}-indole-3-carbonitrile · in 1 record
Experiment against prediction
- 7NLN chain A against the predicted model P9WQ01: TM-score 0.97, RMSD 1.06 Å
- 7NLN chain A against the predicted model P9WQ01: TM-score 0.97, RMSD 1.06 Å
- 7NLN chain B against the predicted model P9WQ01: TM-score 0.97, RMSD 1.10 Å
- 7NLN chain B against the predicted model P9WQ01: TM-score 0.97, RMSD 1.10 Å
- 7NLZ chain A against the predicted model P9WQ01: TM-score 0.96, RMSD 1.34 Å
- 7NLF chain A against the predicted model P9WQ01: TM-score 0.96, RMSD 1.34 Å
- 7NLX chain A against the predicted model P9WQ01: TM-score 0.96, RMSD 1.34 Å
- 7NLX chain A against the predicted model P9WQ01: TM-score 0.96, RMSD 1.34 Å
- 7NNB chain A against the predicted model P9WQ01: TM-score 0.96, RMSD 1.34 Å
- 7NLW chain A against the predicted model P9WQ01: TM-score 0.96, RMSD 1.35 Å
Elsewhere
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