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UniProt P9WPL5

Steroid C26-monooxygenase (P9WPL5)

Steroid C26-monooxygenase (UniProt P9WPL5), EC 1.14.15.28: 2 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P9WPL5
Protein
Steroid C26-monooxygenase
EC
1.14.15.28
Experimental structures
2
Predicted models
1
Ligands
5
Pockets
9 · 2 records with a druggable one

Structures

3 records of P9WPL5 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7QQ7Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with an inhibitor at partial…x-ray diffractionAHEM, BR, CL, EIQ2 (best 0.85)
8A6WCrystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestex-ray diffractionB, EK2B, HEM7 (best 0.85)
P9WPL5AlphaFold monomer V2.0 prediction for steroid C26-monooxygenase (P9WPL5)predictedA——

Ligands

  • HEM · Protoporphyrin IX containing Fe · in 2 records
  • BR · Bromide ion · in 1 record
  • CL · Chloride ion · in 1 record
  • EIQ · ~{N}-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide · in 1 record
  • K2B · (8alpha,9beta)-cholest-4-en-3-one · in 1 record

Experiment against prediction

Elsewhere

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