UniProt P9WN92
Fumarate hydratase class II (P9WN92)
Fumarate hydratase class II (UniProt P9WN92), EC 4.2.1.2: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 39 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WN92
- Protein
- Fumarate hydratase class II
- EC
- 4.2.1.2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 39 · 2 records with a druggable one
Structures
5 records of P9WN92 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5F91 | Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator… | x-ray diffraction | A, B, C, D | 5WJ, CL | 19 (best 0.82) |
| 5F91 | Fumarate hydratase of mycobacterium tuberculosis in complex with formate and allosteric modulator… | x-ray diffraction | A, B, C, D | — | — |
| 5F92 | Fumarate hydratase of Mycobacterium tuberculosis in complex with formate | x-ray diffraction | A, B, C, D | CL | 20 (best 0.82) |
| 5F92 | Fumarate hydratase of mycobacterium tuberculosis in complex with formate | x-ray diffraction | A, B, C, D | — | — |
| P9WN92 | AlphaFold monomer V2.0 prediction for fumarate hydratase class II (P9WN92) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5F92 chain D against the predicted model P9WN92: TM-score 1.00, RMSD 0.46 Å
- 5F92 chain D against the predicted model P9WN92: TM-score 1.00, RMSD 0.46 Å
- 5F92 chain C against the predicted model P9WN92: TM-score 1.00, RMSD 0.58 Å
- 5F92 chain C against the predicted model P9WN92: TM-score 1.00, RMSD 0.58 Å
- 5F91 chain C against the predicted model P9WN92: TM-score 0.96, RMSD 1.83 Å
- 5F91 chain C against the predicted model P9WN92: TM-score 0.96, RMSD 1.83 Å
- 5F91 chain B against the predicted model P9WN92: TM-score 0.96, RMSD 1.85 Å
- 5F91 chain B against the predicted model P9WN92: TM-score 0.96, RMSD 1.85 Å
- 5F91 chain D against the predicted model P9WN92: TM-score 0.95, RMSD 1.76 Å
- 5F91 chain D against the predicted model P9WN92: TM-score 0.95, RMSD 1.76 Å
Elsewhere
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