UniProt P9WN38
Glutamine synthetase 1 (P9WN38)
Glutamine synthetase 1 (UniProt P9WN38), EC 6.3.1.2: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WN38
- Protein
- Glutamine synthetase 1
- EC
- 6.3.1.2
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
3 records of P9WN38 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XYC | Nanomolar inhibitors of mycobacterium tuberculosis glutamine synthetase 1: synthesis, biological… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | 2K9 | 20 (best 0.85) |
| 4XYC | Nanomolar inhibitors of mycobacterium tuberculosis glutamine synthetase 1: synthesis, biological… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | — |
| P9WN38 | AlphaFold monomer V2.0 prediction for glutamine synthetase (P9WN38) | predicted | A | — | — |
Ligands
- 2K9 · 9-phenyl-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one · in 1 record
Experiment against prediction
- 4XYC chain N against the predicted model P9WN38: TM-score 0.97, RMSD 1.20 Å
- 4XYC chain H against the predicted model P9WN38: TM-score 0.97, RMSD 1.20 Å
- 4XYC chain D against the predicted model P9WN38: TM-score 0.97, RMSD 1.21 Å
- 4XYC chain D against the predicted model P9WN38: TM-score 0.97, RMSD 1.21 Å
- 4XYC chain T against the predicted model P9WN38: TM-score 0.97, RMSD 1.22 Å
- 4XYC chain K against the predicted model P9WN38: TM-score 0.97, RMSD 1.21 Å
- 4XYC chain X against the predicted model P9WN38: TM-score 0.97, RMSD 1.22 Å
- 4XYC chain U against the predicted model P9WN38: TM-score 0.97, RMSD 1.22 Å
- 4XYC chain Q against the predicted model P9WN38: TM-score 0.97, RMSD 1.23 Å
- 4XYC chain J against the predicted model P9WN38: TM-score 0.97, RMSD 1.24 Å
Elsewhere
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