UniProt P9WML9
Imidazoleglycerol-phosphate dehydratase (P9WML9)
Imidazoleglycerol-phosphate dehydratase (UniProt P9WML9), EC 4.2.1.19: 7 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P9WML9
- Protein
- Imidazoleglycerol-phosphate dehydratase
- EC
- 4.2.1.19
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 7
Structures
8 records of P9WML9 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XDS | Crystal structure of Mycobacterium tuberculosis HisB bound with an inhibitor | x-ray diffraction | A | MN, CL, 83O | — |
| 5XDS | Crystal structure of mycobacterium tuberculosis hisb bound with an inhibitor | x-ray diffraction | A | MN, CL, 83O | — |
| 5ZQN | Crystal structure of mycobacterium tuberculosis hisb in complex with a ligand | x-ray diffraction | A | MN, CL, IYP | — |
| 7DDV | Crystal structure of M.TUBERCULOSIS imidazole glycerol phosphate dehydratase in complex with an… | x-ray diffraction | A | MN, H3L, CL | — |
| 7DNQ | Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an… | x-ray diffraction | A | MN, CL, HB3 | — |
| 7DNQ | Crystal structure of M.TUBERCULOSIS imidazole glycerol phosphate dehydratase in complex with an… | x-ray diffraction | A | MN, CL, HB3 | — |
| 7FCY | Crystal structure of M.TUBERCULOSIS imidazole glycerol phosphate dehydratase in complex with an… | x-ray diffraction | A | MN, 47Z, CL | — |
| P9WML9 | AlphaFold monomer V2.0 prediction for imidazoleglycerol-phosphate dehydratase (P9WML9) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 7 records
- MN · Manganese (II) ion · in 7 records
- 83O · (2S)-2-azanyl-3-(4H-1,2,4-triazol-3-yl)propanoic acid · in 2 records
- HB3 · 2-(1H-1,2,4-triazol-5-ylsulfanyl)ethanamine · in 2 records
- 47Z · (1S)-2-methyl-1-(2-methyl-1,2,4-triazol-3-yl)propan-1-amine · in 1 record
- H3L · (1S)-1-(2-methyl-1,2,4-triazol-3-yl)ethanamine · in 1 record
- IYP · (2R,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate · in 1 record
Experiment against prediction
- 7DNQ chain A against the predicted model P9WML9: TM-score 0.99, RMSD 0.41 Å
- 7DNQ chain A against the predicted model P9WML9: TM-score 0.99, RMSD 0.41 Å
- 5ZQN chain A against the predicted model P9WML9: TM-score 0.99, RMSD 0.41 Å
- 5XDS chain A against the predicted model P9WML9: TM-score 0.99, RMSD 0.42 Å
- 5XDS chain A against the predicted model P9WML9: TM-score 0.99, RMSD 0.42 Å
- 7DDV chain A against the predicted model P9WML9: TM-score 0.99, RMSD 0.42 Å
- 7FCY chain A against the predicted model P9WML9: TM-score 0.99, RMSD 0.42 Å
Elsewhere
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