UniProt P9WK91
Lipoyl synthase (P9WK91)
Lipoyl synthase (UniProt P9WK91): 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WK91
- Protein
- Lipoyl synthase
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 2 · 1 record with a druggable one
Structures
7 records of P9WK91 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5EXI | Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution | x-ray diffraction | A | SF4, DTV | — |
| 5EXI | Crystal structure of M. tuberculosis lipoyl synthase at 2.28 a resolution | x-ray diffraction | A | — | — |
| 5EXJ | Crystal structure of M. tuberculosis lipoyl synthase at 1.64 A resolution | x-ray diffraction | A | SF4, DTV | — |
| 5EXJ | Crystal structure of M. tuberculosis lipoyl synthase at 1.64 a resolution | x-ray diffraction | A | — | — |
| 5EXK | Crystal structure of M. tuberculosis lipoyl synthase with 6-thiooctanoyl peptide intermediate | x-ray diffraction | A, C, E, G, I, K | F3S, SF4, 5AD, CL | — |
| 5EXK | Crystal structure of M. tuberculosis lipoyl synthase with 6- thiooctanoyl peptide intermediate | x-ray diffraction | A, C, E, G, I, K | — | — |
| P9WK91 | AlphaFold monomer V2.0 prediction for lipoyl synthase (P9WK91) | predicted | A | — | 2 (best 0.84) |
Ligands
Experiment against prediction
- 5EXK chain I against the predicted model P9WK91: TM-score 0.99, RMSD 0.67 Å
- 5EXK chain I against the predicted model P9WK91: TM-score 0.99, RMSD 0.67 Å
- 5EXK chain G against the predicted model P9WK91: TM-score 0.98, RMSD 0.78 Å
- 5EXK chain G against the predicted model P9WK91: TM-score 0.98, RMSD 0.78 Å
- 5EXK chain C against the predicted model P9WK91: TM-score 0.97, RMSD 0.86 Å
- 5EXK chain C against the predicted model P9WK91: TM-score 0.97, RMSD 0.86 Å
- 5EXK chain E against the predicted model P9WK91: TM-score 0.97, RMSD 1.20 Å
- 5EXK chain E against the predicted model P9WK91: TM-score 0.97, RMSD 1.20 Å
- 5EXK chain A against the predicted model P9WK91: TM-score 0.96, RMSD 1.47 Å
- 5EXK chain A against the predicted model P9WK91: TM-score 0.96, RMSD 1.47 Å
Elsewhere
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