UniProt P9WHK9
Orotate phosphoribosyltransferase (P9WHK9)
Orotate phosphoribosyltransferase (UniProt P9WHK9), EC 2.4.2.10: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P9WHK9
- Protein
- Orotate phosphoribosyltransferase
- EC
- 2.4.2.10
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 25 · 2 records with a druggable one
Structures
7 records of P9WHK9 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5HKF | Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex… | x-ray diffraction | A, B | PRP | 4 (best 0.43) |
| 5HKF | Crystal structure of mycobacterium tuberculosis H37RV orotate phosphoribosyltransferase in complex… | x-ray diffraction | A, B | PRP | 4 (best 0.43) |
| 5HKI | Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex… | x-ray diffraction | A, B, C, D | 6ZJ | 6 (best 0.72) |
| 5HKI | Crystal structure of mycobacterium tuberculosis H37RV orotate phosphoribosyltransferase in complex… | x-ray diffraction | A, B, C, D | 6ZJ | 6 (best 0.72) |
| 5HKL | Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex… | x-ray diffraction | A, B | PO4 | 2 (best 0.36) |
| 5HKL | Crystal structure of mycobacterium tuberculosis H37RV orotate phosphoribosyltransferase in complex… | x-ray diffraction | A, B | PO4 | 2 (best 0.36) |
| P9WHK9 | AlphaFold monomer V2.0 prediction for orotate phosphoribosyltransferase (P9WHK9) | predicted | A | — | 1 (best 0.38) |
Ligands
Experiment against prediction
- 5HKL chain A against the predicted model P9WHK9: TM-score 0.99, RMSD 0.57 Å
- 5HKL chain A against the predicted model P9WHK9: TM-score 0.99, RMSD 0.57 Å
- 5HKF chain A against the predicted model P9WHK9: TM-score 0.99, RMSD 0.58 Å
- 5HKF chain A against the predicted model P9WHK9: TM-score 0.99, RMSD 0.58 Å
- 5HKI chain B against the predicted model P9WHK9: TM-score 0.97, RMSD 0.88 Å
- 5HKI chain B against the predicted model P9WHK9: TM-score 0.97, RMSD 0.88 Å
- 5HKI chain A against the predicted model P9WHK9: TM-score 0.95, RMSD 1.41 Å
- 5HKI chain A against the predicted model P9WHK9: TM-score 0.95, RMSD 1.41 Å
- 5HKF chain B against the predicted model P9WHK9: TM-score 0.93, RMSD 0.50 Å
- 5HKF chain B against the predicted model P9WHK9: TM-score 0.93, RMSD 0.50 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.