UniProt P9WGH9
ECF RNA polymerase sigma factor SigH (P9WGH9)
ECF RNA polymerase sigma factor SigH (UniProt P9WGH9): 15 experimental structures and 1 predicted model on GenesisL1, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WGH9
- Protein
- ECF RNA polymerase sigma factor SigH
- Experimental structures
- 15
- Predicted models
- 1
- Pockets
- 26 · 5 records with a druggable one
Structures
16 records of P9WGH9 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZX2 | Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor… | x-ray diffraction | F | — | 6 (best 0.87) |
| 5ZX2 | Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ecf sigma factor… | x-ray diffraction | F | — | — |
| 5ZX3 | Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H | x-ray diffraction | F | — | 5 (best 0.86) |
| 5ZX3 | Mycobacterium tuberculosis RNA polymerase holoenzyme with ecf sigma factor sigma H | x-ray diffraction | F | — | — |
| 6JCX | Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt… | x-ray diffraction | F | — | 8 (best 0.85) |
| 6JCX | Mycobacterium tuberculosis transcription initiation complex with ecf sigma factor sigma H and 6NT… | x-ray diffraction | F | — | — |
| 6JCY | Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF… | x-ray diffraction | F | — | 5 (best 0.85) |
| 6JCY | Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ecf… | x-ray diffraction | F | — | — |
| 6KON | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 5 nt | x-ray diffraction | F | — | — |
| 6KON | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 5 nt | x-ray diffraction | F | — | — |
| 6KOO | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 7 nt | x-ray diffraction | F | — | — |
| 6KOO | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 7 nt | x-ray diffraction | F | — | — |
| 6KOP | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 9 nt | x-ray diffraction | F | — | — |
| 6KOP | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 9 nt | x-ray diffraction | F | — | — |
| 6KOQ | Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-oh RNA of 10 nt | x-ray diffraction | F | — | — |
| P9WGH9 | AlphaFold monomer V2.0 prediction for ecf RNA polymerase sigma factor sigh (P9WGH9) | predicted | A | — | 2 (best 0.55) |
Experiment against prediction
- 6KOP chain F against the predicted model P9WGH9: TM-score 0.50, RMSD 0.82 Å
- 6KOP chain F against the predicted model P9WGH9: TM-score 0.50, RMSD 0.82 Å
- 6JCY chain F against the predicted model P9WGH9: TM-score 0.49, RMSD 1.87 Å
- 6JCY chain F against the predicted model P9WGH9: TM-score 0.49, RMSD 1.87 Å
- 5ZX2 chain F against the predicted model P9WGH9: TM-score 0.48, RMSD 2.21 Å
- 5ZX2 chain F against the predicted model P9WGH9: TM-score 0.48, RMSD 2.21 Å
- 6KOQ chain F against the predicted model P9WGH9: TM-score 0.48, RMSD 0.96 Å
- 6KOO chain F against the predicted model P9WGH9: TM-score 0.46, RMSD 2.22 Å
- 6KOO chain F against the predicted model P9WGH9: TM-score 0.46, RMSD 2.22 Å
- 6KON chain F against the predicted model P9WGH9: TM-score 0.46, RMSD 2.29 Å
Elsewhere
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