UniProt P9WFU9
Lysine--tRNA ligase 1 (P9WFU9)
Lysine--tRNA ligase 1 (UniProt P9WFU9), EC 6.1.1.6: 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WFU9
- Protein
- Lysine--tRNA ligase 1
- EC
- 6.1.1.6
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 4 records with a druggable one
Structures
4 records of P9WFU9 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7QH8 | CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE | x-ray diffraction | A | LYS | 3 (best 0.72) |
| 7QHN | CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE… | x-ray diffraction | A | LYS, C6I | 3 (best 0.73) |
| 7QI8 | CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE… | x-ray diffraction | A | LYS, DD0 | 2 (best 0.73) |
| P9WFU9 | AlphaFold monomer V2.0 prediction for lysine--tRNA ligase 1 (P9WFU9) | predicted | A | — | 3 (best 0.77) |
Ligands
Experiment against prediction
- 7QI8 chain A against the predicted model P9WFU9: TM-score 0.99, RMSD 0.81 Å
- 7QHN chain A against the predicted model P9WFU9: TM-score 0.99, RMSD 0.82 Å
- 7QH8 chain A against the predicted model P9WFU9: TM-score 0.98, RMSD 1.14 Å
Elsewhere
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