UniProt P87074
DNA repair protein CRB2 (P87074)
DNA repair protein CRB2 (UniProt P87074): 8 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P87074
- Protein
- DNA repair protein CRB2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
9 records of P87074 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2VXB | Structure of the Crb2-BRCT2 domain | x-ray diffraction | A, B | — | — |
| 2VXB | Structure of the CRB2-BRCT2 domain | x-ray diffraction | A, B | — | — |
| 2VXC | Structure of the Crb2-BRCT2 domain complex with phosphopeptide. | x-ray diffraction | A, B | — | — |
| 2VXC | Structure of the CRB2-BRCT2 domain complex with phosphopeptide. | x-ray diffraction | A, B | — | — |
| 4BU0 | Crystal structure of Rad4 BRCT1,2 in complex with a Crb2 phosphopeptide | x-ray diffraction | B, C | — | — |
| 4BU0 | Crystal structure of RAD4 BRCT1,2 in complex with a CRB2 phosphopeptide | x-ray diffraction | B, C | — | — |
| 4BU1 | Crystal structure of Rad4 BRCT1,2 in complex with a Crb2 phosphopeptide | x-ray diffraction | C, D | — | — |
| 4BU1 | Crystal structure of RAD4 BRCT1,2 in complex with a CRB2 phosphopeptide | x-ray diffraction | C, D | — | — |
| P87074 | AlphaFold monomer V2.0 prediction for DNA repair protein CRB2 (P87074) | predicted | A | — | 6 (best 0.66) |
Experiment against prediction
- 2VXC chain B against the predicted model P87074: TM-score 0.99, RMSD 0.57 Å
- 2VXC chain B against the predicted model P87074: TM-score 0.99, RMSD 0.57 Å
- 2VXB chain A against the predicted model P87074: TM-score 0.99, RMSD 0.64 Å
- 2VXB chain A against the predicted model P87074: TM-score 0.99, RMSD 0.64 Å
- 2VXB chain B against the predicted model P87074: TM-score 0.99, RMSD 0.65 Å
- 2VXB chain B against the predicted model P87074: TM-score 0.99, RMSD 0.65 Å
- 2VXC chain A against the predicted model P87074: TM-score 0.99, RMSD 0.69 Å
- 2VXC chain A against the predicted model P87074: TM-score 0.99, RMSD 0.69 Å
- 4BU0 chain B against the predicted model P87074: TM-score 0.37, RMSD 1.01 Å
- 4BU0 chain B against the predicted model P87074: TM-score 0.37, RMSD 1.01 Å
Elsewhere
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