UniProt P86287
Actin-1 (P86287)
Actin-1 (UniProt P86287): 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P86287
- Protein
- Actin-1
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 15 · 1 record with a druggable one
Structures
4 records of P86287 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4CBU | Crystal structure of plasmodium falciparum actin I | x-ray diffraction | A | — | — |
| 5OGW | Cryo-EM structure of jasplakinolide-stabilized malaria parasite F-actin at near-atomic resolution | electron microscopy | A, B, C, D, E | ADP, MG, 9UE | 15 (best 0.79) |
| 5OGW | Cryo-EM structure of jasplakinolide-stabilized malaria parasite F- actin at near-atomic resolution | electron microscopy | A, B, C, D, E | ADP, MG, 9UE | — |
| P86287 | AlphaFold monomer V2.0 prediction for actin-1 (P86287) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4CBU chain A against the predicted model P86287: TM-score 0.98, RMSD 0.98 Å
- 5OGW chain D against the predicted model P86287: TM-score 0.96, RMSD 1.59 Å
- 5OGW chain D against the predicted model P86287: TM-score 0.96, RMSD 1.59 Å
- 5OGW chain B against the predicted model P86287: TM-score 0.96, RMSD 1.59 Å
- 5OGW chain B against the predicted model P86287: TM-score 0.96, RMSD 1.59 Å
- 5OGW chain E against the predicted model P86287: TM-score 0.96, RMSD 1.60 Å
- 5OGW chain E against the predicted model P86287: TM-score 0.96, RMSD 1.60 Å
- 5OGW chain C against the predicted model P86287: TM-score 0.96, RMSD 1.60 Å
- 5OGW chain C against the predicted model P86287: TM-score 0.96, RMSD 1.60 Å
- 5OGW chain A against the predicted model P86287: TM-score 0.96, RMSD 1.60 Å
Elsewhere
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